Publications by authors named "Hui-Sheng Yuan"
Objective: To observe postoperative glucose tolerance, gastric inhibitory polypeptide (GIP) , and glucogan-like peptide-1 (GLP-1) in normal glucose level dogs after undergoing gastric bypass procedures, and to explore the mechanism of gastric bypass procedures to treat type 2 diabetes.
Methods: The 6 dogs with normal glucose tolerance had undergone gastric bypass procedures, and measure preoperative and postoperative oral and intravenous glucose tolerance (at time points 1, 2, and 4 weeks) through changes in blood glucose, insulin, gastric inhibitory polypeptide (GIP), glucagon-like peptide-1 (GLP-1), and measure preoperative and postoperative week 4 pancreatic tissue morphology.
Results: Second weeks after operation, the fasting blood sugar was (3.
Article Synopsis
- The study evaluates the use of side-to-side anastomosis between the lesser curvature of the stomach and jejunum during laparoscopic Roux-en-Y gastric bypass in patients with type 2 diabetes.
- A total of 29 patients underwent the procedure without needing to switch to open surgery, and there were no significant complications like bleeding or obstruction after the operation.
- The findings suggest that this method simplifies the procedure, allowing for precise control of the anastomosis size while being easy to learn for surgical teams.
Background: Pancreatic cancer is one of the most aggressive tumors with a dismal prognosis. The membrane cytoskeletal crosslinker Ezrin participates in several functions including cell proliferation, adhesion, motility and survival. There is increasing evidence that Ezrin is overexpressed in vast majority of malignant tumors and regulates tumor progression.
View Article and Find Full Text PDFRadixin, encoded by a gene on chromosome 11, plays important roles in cell motility, invasion and tumor progression. However, its function in pancreatic cancer remains elusive. In this study, radixin gene expression was suppressed with a lentivirus-mediated short-hairpin RNA (shRNA) method.
View Article and Find Full Text PDFObjective: To develop a novel culture system to investigate the effects of ethanol on the function of cultured hepatocytes.
Methods: Sandwich configuration was used to culture hepatocytes and the effects of ethanol on functions of bile excretion and protein synthesis as well as the morphology of cultured hepatocytes were observed.
Results: Bile canaliculi-like structures decreased and anastomatic networks disappeared in ethanol treated hepatocytes.