Publications by authors named "Hui-Shen Liu"
Article Synopsis
- Oral squamous cell carcinoma (OSCC) is strongly linked to areca (betel) chewing among Asians, with several hundred million at risk due to this habit.
- Significant genetic changes, particularly in the CCND1 and CTTN genes located on chromosome 11q13, are observed in nearly half of the OSCC cases studied, indicating their role in cancer development.
- The study suggests a potential for early detection of OSCC using non-invasive brushing methods combined with quantitative PCR analysis to identify gene amplifications in high-risk populations.
