Vaccination significantly reduced the length of SARS-CoV-2 viral clearance: A story from international healthcare workers.

To investigate the impact of vaccines on sociodemographic characteristics, clinical profiles, and outcomes of SARS-CoV-2 infection among healthcare workers in South China during the period of Omicron variant dominance, a retrospective, analytical cross-sectional study was conducted. The findings revealed that while full vaccination could not prevent Omicron variant infection efficiently (26.51% uninfected vs 14.

[Interferon-α mediating the functional damage of CD56CD57natural killer cells in peripheral blood of systemic lupus erythematosuss].

Objective: To investigate the regulatory effect of interferon-α (IFN-α) on the apoptosis and killing function of CD56CD57 natural killer (NK) cells in systemic lupus erythematosus (SLE) patients, and to explore the specific mechanism.

Methods: A total of sixty-four newly treated SLE patients and sixteen healthy controls (HC) enrolled in the Second Hospital of Dalian Medical University were selected as the research subjects. And the gene expression levels of molecules related to NK cell-killing function were detected by real-time quantitative polymerase chain reaction.