Interlayer interaction-force-tuned magnetic responses in Co-tetrazolate-carboxylate system from canted antiferromagnet to field-induced metamagnet.

Interlayer magnetic couplings of low-dimensional magnets have significantly dominated magnetic behavior through skillful regulation of interlayer interacting forces. To identify interaction-force-regulated interlayer magnetic communications, two air-stable Co(II)-based coordination polymers (CPs), a well-isolated layered structure with approximately 12.6 Å interlayer separation and a carboxylate-extended three-dimensional framework with an inter-ribbon distance of 5.

Slow relaxation of Dy(III) single-ion magnets dominated by the simultaneous binding of chelating ligands in low-symmetry ligand-fields.

Electronic effect and geometry distortion of low-symmetry ligand-field on the anisotropy barrier () of spin reversal have been compared in three Dy(III) single-ion magnets through the simultaneous binding of chelating ligands. The substitution of N,O-salicylaldoxime by N,N'-1,10-phenanthroline in the distorted triangular-dodecahedronal field sharply decreases the by 286 K due to an increase in non-preferred transverse anisotropy, while the geometry distortion with CShM = 1.569 went down to 1.

Three microporous metal-organic frameworks assembled from dodecanuclear {NiLn} subunits: synthesis, structure, gas adsorption and magnetism.

Three isostructural heterometallic metal-organic frameworks (MOFs) {[LnNi(OAc)(HL)(L)]·solvent molecules} (HL = 2-hydroxyimino-N-[1-(2-pyrazinyl)ethylidene]-propanohydrazone, Ln = Dy for 1, Tb for 2 and Gd for 3) were solvothermally synthesized by varying rare-earth metal ions with different electron configurations. Their crystal structures, gas adsorption and magnetic behaviors were fully investigated. The three isomorphous MOFs exhibit three-dimensional microporous frameworks with two different orientated dodecane metallic {NiLn(HL)} metallomacrocycles alternately connected by {Ln(L)} connectors, in which an empty one-dimensional channel decorated by the basic hydrazone interior is generated.

High-nuclear heterometallic oxime clusters assembled from triangular subunits: solvothermal syntheses, crystal structures and magnetic properties.

Three series of six pyrazine-2-amidoxime (Hpzaox)-based 3d-4f clusters, {LnNi}, {LnNi} and {LnNi} (Ln = Dy and Gd), were solvothermally synthesized in the absence or presence of different coligands, and were structurally and magnetically characterized. The unusual ring-shaped {Ln(μ-OH)} core in the two {LnNi} complexes is generated by four corner-sharing triangle {Ln(μ-OH)} units, which are further connected to six outer Ni ions by twelve deprotonated Hpzaox ligands in three common binding modes. By contrast, the remaining four clusters contain only two corner-sharing {Ln(μ-OH)} triangles, which interact with peripheral Ni ions through fourteen Hpzaox ligands in five (for {LnNi}) and four (for {LnNi}) different bridging ways.

[Expressions of MACC1, Snail, and KISS-1 Proteins in Infiltrating Breast Carcinoma and Its Clinicopathological Features].

Objectives: To investigate the protein expressions of metastasis-associated in colon cancer 1 (MACC1), KISS-1 (a cancer ruppressor gene) and Snail (the marker of epithelial-mesenchymal transition) in infiltrating breast carcinoma (IBC) and explore the role of them in invasion, metastasis and prognosis in IBC.

Methods: Expressions of MACC1, Snail and KISS-1 were examined by immunohistochemistry in 250 specimens of IBC and 80 specimens of normal breast tissues. Their clinicopathological features were analyzed, and their influence on patients' survival was identified.

LncRNA-MALAT1 Promotes Angiogenesis of Thyroid Cancer by Modulating Tumor-Associated Macrophage FGF2 Protein Secretion.

Tumor-associated macrophages (TAMs) in the tumor microenvironment have been associated with enhanced tumor progression. In this study, we investigated the role and molecular mechanisms of MALAT1 in TAMs derived from thyroid cancer. The expression of MALAT1 and FGF2 in thyroid cancer tissues and cells were measured by quantitative real-time PCR and Western blot.

Magnetic Relaxation Dynamics of a Centrosymmetric Dy Single-Molecule Magnet Triggered by Magnetic-Site Dilution and External Magnetic Field.

A centrosymmetric Dy single-molecule magnet (SMM) and its doped diamagnetic yttrium analogues, DyY and DyY, were solvothermally synthesized to investigate the effects of intramolecular exchange coupling and quantum tunneling of magnetization (QTM) on the magnetic relaxation dynamics. Constructed from two hula-hoop-like Dy ions and a pair of phenoxido groups, the antiferromagnetically coupled Dy exhibits a thermal-activated zero-field effective energy barrier (U) of 277.7 K and negligible hysteresis loop at 2.

MALAT1 promotes the proliferation and invasion of thyroid cancer cells via regulating the expression of IQGAP1.

Background: Increasing evidence indicated that metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) acted as a key regulator in the proliferation and invasion of several cancers. However, the function of MALAT1 in the development of thyroid cancer has not been experimentally established.

Methods: The expression of MALAT1 and IQGAP1 in thyroid cancer tissues and cells were detected by quantitative real-time PCR and western blot.

Quality of life and cosmetic result of single-port access endoscopic thyroidectomy via axillary approach in patients with papillary thyroid carcinoma.

Background: Endoscopic thyroidectomy for minimally invasive thyroid surgery has been widely applied in the past decade. The present study aimed to evaluate the effects of single-port access transaxillary totally endoscopic thyroidectomy on the postoperative outcomes and functional parameters, including quality of life and cosmetic result in patients with papillary thyroid carcinoma (PTC).

Patients And Methods: Seventy-five patients with PTC who underwent endoscopic thyroidectomy via a single-port access transaxillary approach were included (experimental group).

A novel oxime-derived 3d-4f single-molecule magnet exhibiting two single-ion magnetic relaxations.

A new oxime-derived {DyNi} cluster with a paramagnetic butterfly-shaped Dy core and peripheral diamagnetic planar-square Ni(II) ions was solvothermally synthesized. The weak ferromagnetically coupled cluster exhibits field-induced single-molecule magnetic behavior with two thermally activated single-ion relaxations.

[Efficacy of modified radical operation of preserving nipple-areolar complex on early stage breast cancer].

Background And Objective: Modified radical mastectomy of preserving nipple-areolar complex (NAC) is an important surgical therapy for stage I-IIa breast cancer, but the oncological risk is controversial. This study was to compare the efficacy of NAC-preserving modified radical operation and conventional modified radical operation on early stage breast cancer.

Methods: The patients who received NAC-preserving modified radical operation (42 patients) or conventional modified radical operation (84 patients) from January 1998 to December 2003 in the First Affiliated Hospital of Bengbu Medical College were matched with a ratio of 1:2 by age at diagnosis, axillary lymph node status, sexual hormone receptor status, tumor size and Her-2/neu expression for retrospective analysis.

[Clinicopathologic analysis of the nipple-areolar complex occult involvement in early stage breast carcinoma].

Objective: The aim of this study was to investigate the incidence of nipple-areola complex (NAG) involvement in stage I - II a breast cancer patients who underwent skin-sparing mastectomy and to determine the associated risk factors, to provide a theoretical basis for modified radical mastectomy preserving NAC and breast reconstruction in early stage breast cancer patients.

Methods: A total of 68 women with primary breast cancer were included in this study. The following associated risk factors of NAC involvement were assessed and compared with those of non-involvement: the distance from the tumor site to the edge of areola (D), axillary lymph node status, over-expression of HER-2/neu, location of tumor, TNM stage, abnormal nipple (nipple indentation, erosion, discharge), tumor size, age, histological type, as well as status of estrogen receptor (ER) and progesterone receptor (PR), by Chi-square test.

Dominant-negative E-cadherin inhibits the invasiveness of inflammatory breast cancer cells in vitro.

E-cadherin is a transmembrane glycoprotein which mediates epithelial cell-to-cell adhesion function as a tumor suppressor and frequently loss of expression in a wide spectrum of human cancer. However, recent studies demonstrated that E-cadherin was always over-expressed in inflammatory breast cancer (IBC) specimen and cell lines, which is a clinical extreme malignancy of breast cancer. It is hypothesized that the gain and not the loss of the E-cadherin axis contributes to the IBC unique phenotype.

[Biological significance of E-cadherin in an inflammatory breast carcinoma cell line].

Objective: To investigate the effects of E-cadherin on the biologic behavior of SUM149, an inflammatory breast cancer cell line.

Methods: SUM149 cells were transfected with dominant-negative mutant E-cadherin expressing plasmid. The positive clones with higher expression of dominant-negative E-cadherin mutant were identified by RT-PCR and fluorescent flow cytometry method.