Publications by authors named "Hui-Lin Leng"

Article Synopsis
  • CEGI injection, made from rabbit muscle extract and cattle brain gangliosides, is used as a neuroprotectant for nerve injuries, but more clinical evidence is needed to support its efficacy.
  • A study involving 319 patients with acute cerebral infarction in China scrutinized CEGI's effects in a randomized placebo-controlled trial over 14 days.
  • Results indicated that patients receiving CEGI had better outcomes and reduced disabilities compared to the placebo group, with particularly significant improvements in those with moderate stroke.
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To perform a meta-analysis to help resolve the controversy of whether the Angiogenin (ANG) rs11701 polymorphism is associated with amyotrophic lateral sclerosis (ALS) risk. A literature search of PubMed, Embase, Web of Science, Chinese National Knowledge Infrastructure, Wanfang and SinoMed was conducted for eligible studies published up to Jun 5, 2015. The strength of the association between the polymorphism and ALS susceptibility was estimated by odds ratio (OR) and associated 95 % confidence interval (CI).

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Purpose: To perform a meta-analysis to help resolve the controversy of whether the ATP13A2 A746T variant is associated with Parkinson's disease (PD) susceptibility in Han Chinese.

Methods: Six literature databases were searched for case-control studies published up to October 2014: Web of Science, PubMed, Embase, Chinese National Knowledge Infrastructure, Wanfang and SinoMed.

Results: Five eligible articles were identified, which reported six case-control studies and a total of 1703 cases and 2050 controls.

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