- The study aimed to evaluate the impact of dihydromyricetin (DHM) on obesity caused by a high-fat diet in mice and investigate its role in promoting the browning of white adipose tissue (WAT).
- A total of 60 mice were divided into six groups, some receiving a high-fat diet and others treated with varying doses of DHM, followed by assessments of body weight, blood glucose, and adipose tissue characteristics after 16 weeks.
- Results indicated that DHM treatment in high-fat diet mice effectively reduced body weight, fat accumulation, and blood glucose levels while enhancing the expression of uncoupling protein 1 (UCP1), suggesting a potential mechanism for its anti-obesity