Publications by authors named "Hui-Hui Ti"
Article Synopsis
- This research focuses on a new self-delivery nanomedicine called CeCe, made from a photosensitizer (chlorin e6) and an autophagy promoter (celastrol) to enhance photodynamic therapy (PDT) against tumors.
- CeCe works by producing reactive oxygen species (ROS) when exposed to light, which increases oxidative stress in tumor cells and promotes autophagy, ultimately leading to enhanced cell death.
- In animal experiments, CeCe showed better tumor control compared to using chlorin e6 or celastrol alone, indicating a strong combined effect of promoting autophagy while delivering PDT for improved cancer treatment.
Further investigation on the stems of Artocarpus nitidus subsp. lingnanensis led to the isolation and characterization of a new flavan-3-ol, named artoflavanocoumarin, along with three known compounds (+)-catechin, (+)-afzelechin 3-O-α-L-rhamnoside, and (+)-catechin 3-O-α-L-rhamnoside. Their structures were elucidated on the basis of spectroscopic data.
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