[Correlations of salivary ion concentration, Streptococcus and Bifidobacterium in children with caries].

Purpose: To analyze the correlation between the changes in salivary ion concentration, Streptococcus and Bifidobacterium in children with dental caries and the severity of the disease.

Methods: Eighty children with dental caries treated from May 2022 to April 2023 were selected as the experimental group. According to the DMFT, they were divided into mild group (DMFT≤15%, n=35) and severe group (DMFT>15%, n=45).

Anti-Inflammatory Ergosteroid Derivatives from the Coral-Associated Fungi HL-44.

To obtain the optimal fermentation condition for more abundant secondary metabolites, Potato Dextrose Agar (PDA) medium was chosen for the scale-up fermentation of the fungus HL-44 associated with the soft coral . The EtOAc extract of the fungi HL-44 was subjected to repeated column chromatography (CC) on silica gel and Sephadex LH-20 and semipreparative RP-HPLC to afford a new ergostane-type sterol ester () together with fifteen derivatives (-). Their structures were determined with spectroscopic analyses and comparisons with reported data.