Organoids, exhibiting the capability to undergo differentiation in specific in vitro growth environments, have garnered significant attention in recent years due to their capacity to recapitulate human organs with resemblant in vivo structures and physiological functions. This groundbreaking technology offers a unique opportunity to study human diseases and address the limitations of traditional animal models. Cardiovascular diseases (CVDs), a leading cause of mortality worldwide, have spurred an increasing number of researchers to explore the great potential of human cardiovascular organoids for cardiovascular research.
View Article and Find Full Text PDFZhongguo Xue Xi Chong Bing Fang Zhi Za Zhi
April 2014
Objective: To evaluate the effects of the schistosomiasis control mode ("Hubei mode") that includes "comprehensive measures in a whole endemic county", "co-action of Health Ministry and Province" and "replacing cattle with machine" in Hubei Province.
Methods: The data of schistosomiasis control in Hubei Province from 2008 to 2012 were collected and a database including the annual schistosome infections of human and cattle, acute schistosome infection, outbreak of schistosomiasis endemic, schistosome infected Oncomelania hupensis snails, and other prevention indicators was established and analyzed by using SPSS.
Results: Compared with 2008, in 2012, the infection rates declined by 64.
Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi
June 2011
The status of schistosomiasis transmission control in Hongshan District of Wuhan City was evaluated. The schistosome infection rates of human and cattle were both below 1%, no local acute schistosomiasis patient occurred, and infected snails were not found during the period of 2008 to 2010. The files and data were well-documented.
View Article and Find Full Text PDFThe great progress made in the control of schistosomiasis japonica in China is to some extent explained by successful intermediate host snail control, in particular with environmental management commencing some 50 years ago. By 1995, interruption of Schistosoma japonicum transmission had been achieved in five of the 12 schistosome-endemic provinces while endemic areas in the remaining provinces had been reduced significantly, and snail habitats had decreased by 74%. In this paper, we review the role and approaches towards control and give an account of compounds toxic to snails.
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