[Transfer RNAs inhibit the growth of L929 cells in vitro].

Aim: To explore the effects of tRNA on the growth of mammalian cells.

Methods: L929, NIH3T3, MCF-7 and PC12 cells were seeded in 96 well culture plate individually, and incubated at 37 degrees C in 5% CO2 for 4 h, the tRNAs from different species were added to the culture media individually. After certain time of incubation, the viability of the cells was evaluated by the MTT methods.