Publications by authors named "Hui-Biao Li"

There were no systematic researches about autophagy-related long noncoding RNA (lncRNA) signatures to predict the survival of patients with colon adenocarcinoma. It was necessary to set up corresponding autophagy-related lncRNA signatures. The expression profiles of lncRNAs which contained 480 colon adenocarcinoma samples were obtained from The Cancer Genome Atlas (TCGA) database.

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Objective: Ulcerative colitis (UC), one of the most stubborn diseases, is mainly treated by aminosalicylic acid (ASA). However, the side effects of ASA include vomiting, nausea, rash, diarrhea, headache, etc, which seriously affect life-quality of UC patients. Probiotics such as bifid triple viable (BTV) could reduce drug-induced adverse reactions and has a good clinical effect on UC.

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Article Synopsis
  • The meta-analysis investigates the link between Helicobacter pylori (H pylori) and periodontal disease (PD) using data collected from various studies.
  • The analysis included 13 studies with a total of 6,800 patients, finding that individuals with oral H pylori had a 2.31 times higher odds of developing PD compared to those without.
  • The findings indicate a significant association between H pylori and PD, particularly among gastric disease patients, but calls for more comprehensive studies to further validate these results.
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Introduction: NRAS gene is associated with malignant proliferation and metastasis of colorectal cancer (CRC). But its prognostic value on CRC is still unknown. The objective of this study is to perform a meta-analysis to obtain its prognostic value on survival of CRC patients.

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Article Synopsis
  • DNA mismatch repair is believed to significantly influence the progression and outcomes of colorectal cancer, but its exact prognostic value remains unclear.
  • A systematic review of 21 studies assessed the relationship between mismatch repair deficiency and patient survival, finding that those with such deficiencies had lower overall and disease-free survival rates.
  • The analysis revealed that mismatch repair deficiency correlates with better prognosis in both Asian and Western populations, suggesting its potential as a valuable prognostic marker in colorectal cancer patients.
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Background: To systematically evaluate the clinical efficacy and safety of Kangfuxin liquid (KFXL) combined with aminosalicylic acid (ASA) in treating ulcerative colitis (UC).

Methods: The PubMed, Cochrane Library, Embase, CBM, Wan fang, the Chinese Scientific Journal Database (VIP), and Chinese National Knowledge Infrastructure (CNKI) databases were systematically searched for randomized controlled trials of KFXL combined with ASA for UC from the inception dates to March 3, 2017. Two researchers independently screened the literature, extracted data, and evaluated the methodological quality according to the inclusion criteria.

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