Publications by authors named "Hui Zhen Cheng"
Background: Living guidelines contain continually updated, and potentially changing, clinical recommendations. The implications of living guidelines for consumers (e.g.
View Article and Find Full Text PDFA prolific multi-product sesterterpene synthase CbTPS1 is characterized from the medicinal Brassicaceae plant Capsella bursa-pastoris. Twenty different sesterterpenes including 16 undescribed compounds, possessing 10 different mono-/di-/tri-/tetra-/penta-carbocyclic skeletons, including the unique 15-membered macrocyclic and 24(15→14)-abeo-capbuane scaffolds, are isolated and structurally elucidated from engineered Escherichia coli strains expressing CbTPS1. Site-directed mutagenesis assisted by molecular dynamics simulations resulted in the variant L354M with up to 13.
View Article and Find Full Text PDFFive new secoiridoids, gentianopsins A-E (1-5), along with two known analogues (6 and 7) were isolated from the whole plants of the medicinal herb Gentianopsis barbata. Their structures were elucidated by a comparison of extensive spectroscopic analysis (1D and 2D NMR, and HRMS) and quantum chemical calculations. Gentianopsins A (1) and B (2) represented two unusual skeletons of trihomo-secoiridoids.
View Article and Find Full Text PDFArticle Synopsis
- The research investigates the origins, diversification, and demographic history of the O1a-M119 lineage over the past 10,000 years, focusing on its impact on East and Southeast Asian populations, particularly the Han, Tai-Kadai, and Austronesian groups.
- The study utilized Y-chromosome sequences, including both new and previously collected data, to create a revised phylogenetic tree and analyze the geographic distribution of O1a-M119 sub-lineages among Chinese males.
- Findings reveal the continuous expansion of O1a-M119 and suggest a shared ancestry among the studied populations during the Neolithic Age, while highlighting the complexity of paternal genetic divergence across regions.
Article Synopsis
- The study focuses on the Y-chromosome haplogroup C2a-L1373, which is significant in tracing paternal lineages in northern Asia and Native American populations.
- Using DNA sequences from rare subbranches and ancient individuals, researchers constructed phylogenetic trees to analyze the haplogroup's origins and expansion.
- Results suggest that C2a-L1373 expanded after the last glacial maximum, revealing two potential migration waves and supporting theories that Native Americans are descended from "Ancient Northern Siberians" and other populations that emerged during that time.
Article Synopsis
- Recent studies have focused on the genetic diversity of Han Chinese, particularly the north-south genetic differences, but there has been less research on central Han Chinese, specifically from Hubei province.* -
- Researchers collected genetic samples from 122 individuals in Hubei, analyzing 534,000 SNPs, and found that Hubei Han are genetically between northern and southern Han Chinese, with no significant substructure among the seven sampled counties.* -
- The study indicates that the genetic makeup of Hubei Han is a mix of about 63% from southern indigenous populations (Tai-Kadai or Austronesian) and 37% from northern populations (Tungusic or Mongolic), highlighting Hubei's
Article Synopsis
- The study examines the genetic diversity and ancestry of Mongolian and Kazakh populations, highlighting the ethnic variations based on geographic and tribal differences.
- By analyzing over 690,000 genetic markers from individuals, researchers identified distinct genetic clusters in Mongolians and found significant ancestry from both West Eurasian and East Asian groups, particularly from Bronze Age and Neolithic populations.
- The results suggest that the genetic landscape of these populations has been shaped by historical migrations, admixture events, and agricultural expansion over the past several centuries.
Article Synopsis
- This study investigates the origins and differentiation of Austronesian populations and their languages, focusing on the paternal lineage of Malays in Southeast Asia and their separation from related Asian groups like the Daic and Austro-Asiatic populations.
- Researchers analyzed Y-chromosome sequences from 50 Malays and 200 other related individuals, discovering six major paternal lineages with a similar expansion timeline dating back 5,000 to 6,000 years ago.
- The findings support theories by prior researchers about the common ancestry of Austronesians, showing that the emerging paternal lineages likely coincide with the early differentiation of modern Austronesian populations.
Objectives: Haplogroup C2a-M48 is the predominant paternal lineage of Tungusic-speaking populations, one of the largest population groups in Siberia. Up until now, the origins and dispersal of Tungusic-speaking populations have remained unclear. In this study, the demographic history of Tungusic-speaking populations was explored using the phylogenetic analysis of haplogroup C2a-M86, the major subbranch of C2a-M48.
View Article and Find Full Text PDFHuman Y-chromosome haplogroup C2b-F1067 is one of the dominant paternal lineages of populations in Eastern Eurasia. In order to explore the origin, diversification, and expansion of this haplogroup, we generated 206 new Y-chromosome sequences from C2b-F1067 males and coanalyzed 220 Y-chromosome sequences of this haplogroup. BEAST software was used to reconstruct a revised phylogenetic tree of haplogroup C2b-F1067 with age estimates.
View Article and Find Full Text PDFArticle Synopsis
- More research is needed to understand the genetic diversity of Han populations across different regions in China, particularly in Henan province, which has historical significance as part of the ancient Huaxia.
- The study involved sequencing Y chromosomes from 60 males in Zhengzhou and revealed a high diversity of paternal lineages, indicating complex admixture over time.
- Findings suggest that the genetic diversity in modern Han populations is largely due to many ancient lineages from the Palaeolithic age, alongside a more recent expansion of a few predominant lineages.
Bai and Yi people are two Tibeto-Burman speaking ethnic groups in Yunnan, southwest China. The genetic structure and history of these two groups are largely unknown due to a lack of available genetic data. To investigate the paternal genetic structure and population relationship of the Yi and Bai people.
View Article and Find Full Text PDFPrevious studies have suggested that the human Y-chromosome haplogroup Q1a1a-M120, a widespread paternal lineage in East Asian populations, originated in South Siberia. However, much uncertainty remains regarding the origin, diversification, and expansion of this paternal lineage. To explore the origin and diffusion of paternal Q-M120 lineages in East Asia.
View Article and Find Full Text PDF[Investigation of production status in major wolfberry producing areas of China and some suggestions].
Zhongguo Zhong Yao Za Zhi
June 2014
Article Synopsis
- - The study aimed to analyze the production status and safety factors impacting wolfberry quality in China, with investigations conducted during specific periods in 2009 and 2013.
- - Key factors examined included fertilizing methods, pesticide use, and early processing techniques of wolfberry.
- - Based on the findings, the study offered recommendations for improvement to the management and production sectors related to wolfberry cultivation.
[Screening for virulence strains of Metarhizium against Dorysthenes hydropicus pascoes].
Zhongguo Zhong Yao Za Zhi
October 2013
Objective: The aim of the present study was to screen the Metarhizium strains with high virulence against the larvae of Dorysthenes hydropicus, a serious pest of Citrus grandis.
Method: Thirty six strains of Metarhiziums were isolated from the soil of C. grandis GAP base and collected from other institutions, and the pathogenicity of these strains against 1st instar larvae of D.
[Primary studies on biological characteristics of Dorysthenes hydropicus].
Zhongguo Zhong Yao Za Zhi
December 2008
Article Synopsis
- - The study focuses on the biological traits of Dorysthenes hydropicus within Cirtus grandis farms to provide evidence for its management and control.
- - The research discovered that D. hydropicus reproduces every 1-2 years, overwinters as larvae, and exhibits a significant population size, with females capable of laying up to 543 eggs, mainly hatching late June to early July.
- - The findings indicate that D. hydropicus poses a significant threat to Cirtus grandis, leading to the death of thousands of trees annually, highlighting the need for effective prevention strategies.
[Study on reproduction biology of Cistanche deserticola--seedling emergence and flowering].
Zhongguo Zhong Yao Za Zhi
September 2007
Article Synopsis
- The study aimed to investigate the reproduction characteristics of Cistanche deserticola, focusing on its growth dynamics in a Ningxia plantation.
- Results showed that germination occurs within the first ten days of the month, followed by a flowering period lasting about a month, and that the levels of boschnaloside and echinacoside decline during this reproduction phase.
- The conclusion indicates that C. deserticola has a reproduction period of approximately two months, with germination being the optimal time for harvesting.
Article Synopsis
- The study focused on the pest Loxostege stieticatis, which poses a significant threat to Haloxylon ammodendron plants.
- Research indicated that it can be effectively managed using less harmful pesticides like deltametrin.
- Implementing non-toxic control measures in the field is recommended for dealing with this pest.
[Study on residue analysis method of imidacloprid in Ephedrae sinica].
Zhongguo Zhong Yao Za Zhi
April 2007
Article Synopsis
- The objective of the study was to develop a reliable method to analyze imidacloprid residue in Ephedra sinica using High-Performance Liquid Chromatography (HPLC).
- The method involved extracting imidacloprid with dichloromethane, purifying it with a chromatography column, and separating it on a Spherisorb C18 column using a methanol-water mixture for detection at 270 nm.
- The results indicated that the method had a low limit of detection and quantification, with recovery rates between 85.37%-90.65% and a low standard deviation, demonstrating its effectiveness for pesticide residue analysis.
[Study on the stigma/pollen vigor and self-compatibility of Platycodon grandiflorum].
Zhongguo Zhong Yao Za Zhi
March 2006
Article Synopsis
- The study aimed to gather essential data for breeding and cultivation of Platycodon grandiflorum, focusing on pollination and pollen viability.
- Research involved field investigations and bagging techniques for pollination, using TTC solution to assess pollen vigor, which started at 81.4% and dropped to 27.6% over three days.
- Results indicated that optimal pollination occurs 4-6 days post-petal opening, with low self-pollination rates due to mismatched maturation of reproductive parts, while hand pollination improved compatibility rates significantly.
[Study on yield and quality of Scutellaria baicalensis from different habitats].
Zhongguo Zhong Yao Za Zhi
April 2005
Article Synopsis
- The study aimed to compare the economic and yield characteristics, as well as the major active ingredient content, of Scutellaria baicalensis from various habitats.
- Researchers conducted a field test using randomized block design and performed analyses like variance, correlation, and quality assessment.
- Results indicated notable differences in both yield and quality of the crude drugs, with the highest quality coming from Pingyi in Shandong province.
Objective: To investigate the factors influencing the seed germination of Bupleurum chinense and B. falcatum.
Method: The seeds of different maturity, and the seeds whose coat were removed or nicked before dipping in water, were germinated in a light growth chamber.
Objective: To study the Biological effect of seed-coating in Carthamus tinctorins.
Method: Two kinds of seedcoating chemicals SCF1 and SCF2 were used in this experiment, the seed YM-99 and 27981-99 were coated by three kinds of ratio of seedcoating chemicals to seed. It was investigated that the germination energy and germination percentage in the room and the emergence rate, seedling stage growing, pest in the field.
[Applied studies of biological control techniques on healthful Chinese crude drugs].
Zhongguo Zhong Yao Za Zhi
August 2003
Medicinal plants always suffer from diseases and pests in their cultivation and growing, and the yield and quality are reduced. At present, chemical pesticide is mainly used to control the diseases and pests. The long-term use and over-use of pesticide result in pesticide residue, pests resistance to pesticide, water and soil pollution and other environmental contamination.
View Article and Find Full Text PDF[Study on the pollination characteristic of Cistanche deserticola].
Zhongguo Zhong Yao Za Zhi
June 2003
Objective: To study the Pollination Characteristic of C. deserticola.
Method: Four pollination methods were used, cross pollination coming different plant, cross pollination in one plant, wind pollination and no-pollination.