Prognostic and clinicopathological role of pretreatment systemic inflammation response index (SIRI) in gastric cancer: a systematic review and meta-analysis.

Background: The systemic inflammatory response index (SIRI) is calculated via the following formula: SIRI = monocyte count × neutrophil count/lymphocyte count. The value of the SIRI in predicting the prognosis of gastric cancer (GC) remains controversial. This study revealed the precise effect of the SIRI in predicting GC prognosis through a meta-analysis.

Role of surgical vaginoscopy through no-touch hysteroscope in the treatment of female reproductive polyps.

Background: The study aims to investigate the application of surgical vaginoscopy via a no-touch hysteroscopic approach for the management of female genital polyps. The primary objective is to assess the feasibility of this technique in treating intrauterine pathologies in both pregnant and non-pregnant women.

Methods: A total of forty-six patients diagnosed with genital polyps underwent operative vaginoscopy at a university-affiliated hospital between April 1, 2017 and May 31, 2023.

[Standard establishment and item list for conducting and reporting rapid review in traditional Chinese medicine].

This study aims to establish the standard items for conducting and reporting rapid review(RR) in traditional Chinese medicine(TCM) and promote the RR transparency in TCM. First, the basic standard items of conducting and reporting RR were reviewed, on the basis of which the basic RR implementation methods and steps were summarized. The initial item pool of RR implementation and reporting standards in TCM was established with the Delphi method.

Comparative efficacy and safety of Chinese patent medicines for primary insomnia: a systematic review and network meta-analysis of 109 randomized trials.

Ethnopharmacological Relevance: Chinese patent medicine (CPM) is formulated using Chinese herbal medicines as raw materials according to prescribed methods and preparation processes. It is one of the most commonly used complementary and alternative therapies for insomnia in China. Dozens of CPMs have been applied in clinical settings to treat primary insomnia, and ample evidence has proven the efficacy and safety of various CPMs.

Cyanidin-3-rutinoside from Mori Fructus ameliorates dyslipidemia via modulating gut microbiota and lipid metabolism pathway.

Dyslipidemia is responsible for pathologies of cardiovascular diseases and gut microbiota plays an essential role in lipid metabolism. Dietary supplementation is an important supplement to medicine in management of dyslipidemia. Mori Fructus is a popular Asia medical food with various pharmacological benefits including anti-hyperlipidemia.

Recovery effects of the long-term cryopreserved Anammox sludge by adjusting the sludge amount.

Anammox process was one of the most promising nitrogen removal technologies. This study investigated the recovery performance of Anammox sludge after 83 days of cryopreservation in two reactors (R1 and R2). Reactor R1 utilized Anammox sludge pretreated with low-substrate simulated wastewater prior to long-term cryopreservation, and successful recovery was achieved by discharging sludge under ammonia nitrogen concentrations of 100 mg/L.

Characteristics of Meat from Farmed Sika Deer () and the Effects of Age and Sex on Meat Quality.

This study assessed the meat quality of Sika deer () from various age and sex groups using the longissimus dorsi (LD) muscle. Samples from different age groups (2, 3, and 4 years old) were analyzed for various parameters. The results show that, with increasing age, there is a decrease in moisture and drip loss ( < 0.

Serum transgelin is a novel prognostic biomarker for COVID-19 patients.

Background: Transgelin is a central actin-binding protein of the calponin family and involved in the process of multiple pulmonary diseases. Nevertheless, the role of transgelin in Coronavirus disease 2019 (COVID-19) patients is confusing.

Methods: All 317 COVID-19 patients were recruited from two hospital.

Spatiotemporal distribution of chlorophyll-a concentration in the south China sea and its possible environmental regulation mechanisms.

In this paper, the spatial and temporal distribution of chlorophyll-a (Chl-a) concentration in the South China Sea (SCS) and its major environmental regulator mechanisms were studied by using satellite remote sensing data sea surface temperature (SST), sea surface wind (SSW), and aerosol optical depth (AOD) spanning from January 2000 to December 2022. The results show that Chl-a in the SCS exhibit notable spatio-temporal variations: they peak in winter (∼0.234 mg m) and autumn (∼0.

Regnase-1 regulates inflammation in T cells of ankylosing spondylitis through the TRAF6.

The study aimed to investigate the regulatory role of Regnase-1 in ankylosing spondylitis (AS) inflammation. We collected 10 ml peripheral venous blood and epidemiological data from 45 AS patients and 45 healthy controls and performed enzyme-linked immunosorbent assay (ELISA) experiments to measure the levels of inflammatory cytokines. Then CD3 + T lymphocytes were isolated by magnetic bead sorting method, and the transcriptional levels of Regnase-1 and TNF receptor-associated factor 6 (TRAF6) were detected by real-time quantitative PCR (qRT-PCR).

Emotional salience network involved in constructing two-dimensional fear space in humans.

Fear learning is pivotal for organismal survival, ensuring the ability to avoid potential threats through learning based on experiencing minimal fear information. In reality, fear learning requires to form a structured representation of fear experiences from multiple dimensions in order to support flexible use in ever-changing environment. Yet, the underlying neural mechanisms of constructing dimensional fear space remain elusive.

Real-time identification of multi-component periodic signals using Online Harmonics Extraction Approach.

To identify the frequency and amplitude of a periodic signal in real-time, a novel approach termed the "Online Harmonics Extraction Approach (OHEA)" is proposed in this paper. This method employs a notch filter with an adjustable center frequency to identify the frequency of periodic signals accurately. The computation of the envelope curve and phase-sensitive detection are combined to identify the signal amplitude and smooth out transient stages.

Diet-gut microbiome interaction and its impact on host blood glucose homeostasis: a series of nutritional n-of-1 trials.

Background: The interplay between diet and gut microbiome substantially influences host metabolism, but uncertainties remain regarding their relationships tailored for each subject given the huge inter-individual variability. Here we aim to investigate diet-gut microbiome interaction at single-subject resolution and explore its effects on blood glucose homeostasis.

Methods: We conducted a series of nutritional n-of-1 trials (NCT04125602), in which 30 participants were assigned high-carbohydrate (HC) and low-carbohydrate (LC) diets in a randomized sequence across 3 pair of cross-over periods lasting 72 days.

Physiological activities, transcriptomes and metabolomes of Pyropia yezoensis conchocelis unveil the roles of pyPGK, pyBCKDHA, and pyDLD in response to freshwater soaking.

Freshwater soaking of the conchocelis is often used to reduce yellow spot, white spot, and mud red disease in Pyropia yezoensis. However, the understanding of physiological, transcriptomic, and metabolomic changes for the conchocelis under freshwater stress remains limited. Here, we comprehensively explored the dynamic changes of physiological activities, transcriptomes, and metabolomes of the conchocelis under three points of freshwater stress (0 h, 4 h, and 24 h) and one point of seawater recovery (R2h).

Comparing ultrasound-guided intra-articular injection and medial branch block for lumbar facet joint pain: a clinical study.

Purpose: This study aims to compare the effectiveness of ultrasound-guided intra-articular (IA) injections with medial branch nerve blocks in treating lumbar facet joint pain.

Methods: This retrospective study enrolled 94 patients clinically diagnosed with lumbar facet joint pain. Diagnostic blocks confirmed the diagnosis in 82 patients, evidenced by a pain visual analog score (VAS) reduction of at least 50% immediately following the injection.

School Connectedness and Academic Burnout in Middle School Students: A Multiple Serial Mediation Model.

Higher levels of school connectedness are associated with better study habits, but their relationship with academic burnout and the underlying mechanisms have not been revealed. We used a questionnaire to investigate the relationship between school connectedness and academic burnout and the mediating mechanisms of burnout in a sample of 394 Chinese middle school students, controlling for class, gender, and grade level. The results revealed that (1) school connectedness, autonomous motivation to learn, and core self-evaluations were significantly negatively related to academic burnout; and that (2) academic self-handicapping, core self-evaluations, and autonomous motivation to learn individually mediated the effects of school connectedness on academic burnout and mediated the effects of multiple factors.