Postsynaptic lncRNA Sera/Pkm2 pathway orchestrates the transition from social competition to rank by remodeling the neural ensemble in mPFC.

Individuals' continuous success in competitive interactions with conspecifics strongly affects their social hierarchy. Medial prefrontal cortex (mPFC) is the key brain region mediating both social competition and hierarchy. However, the molecular regulatory mechanisms underlying the neural ensemble in the mPFC remains unclear.

Social isolation reinforces aging-related behavioral inflexibility by promoting neuronal necroptosis in basolateral amygdala.

Aging is characterized with a progressive decline in many cognitive functions, including behavioral flexibility, an important ability to respond appropriately to changing environmental contingencies. However, the underlying mechanisms of impaired behavioral flexibility in aging are not clear. In this study, we reported that necroptosis-induced reduction of neuronal activity in the basolateral amygdala (BLA) plays an important role in behavioral inflexibility in 5-month-old mice of the senescence-accelerated mice prone-8 (SAMP8) line, a well-established model with age-related phenotypes.

Development and feasibility testing of an avatar-based education application for patients with acute coronary syndrome.

Aims: To develop and evaluate an interactive, avatar-based education application, for improving patients' knowledge of, and response to, acute coronary syndrome (ACS) symptoms.

Background: A patient's ability to recognise and respond to the symptoms of ACS is imperative for seeking timely medical intervention. Innovative patient education interventions are needed to support patient education and patient self-care.

Effectiveness of using avatar-based technology in patient education for the improvement of chronic disease knowledge and self-care behavior: a systematic review protocol.

The objective of this review is to investigate the effectiveness of using avatar-based technology in patient education for the improvement of knowledge and self-care behaviors for chronic disease.

Self-efficacy: a useful construct to promote physical activity in people with stable chronic heart failure.

Aim: To explore the conceptual underpinnings of self-efficacy to address the barriers to participating in physical activity and propose a model of intervention.

Background: The benefits of physical activity in reducing cardiovascular risk have led to evidence-based recommendations for patients with heart disease, including those with chronic heart failure. However, adherence to best practice recommendations is often suboptimal, particularly in those individuals who experience high symptom burden and feel less confident to undertake physical activity.

Health-seeking beliefs of cardiovascular patients: a qualitative study.

Objectives: The study aims were to (a) describe the experiences of Chinese Australians with heart disease following discharge from hospital for an acute cardiac event; (b) identify patterns and cultural differences of Chinese Australians following discharge from hospital; and (c) illustrate the illness/health seeking behaviors and health beliefs of Chinese Australians.

Design: Qualitative study.

Methods: Interview data were obtained from the following sources: (a) focus groups of Chinese community participants without heart disease; (b) interviews with patients recently discharged from hospital following an admission for an acute cardiac event; and (c) interviews with Chinese-born health professionals working in Australia.

Value of Web-based learning activities for nursing students who speak English as a second language.

There is an increasing need to address the educational needs of students with English as a second language. The authors assessed the value of a Web-based activity to meet the needs of students with English as a second language in a bioscience subject. Using telephone contact, we interviewed 21 Chinese students, 24 non-Chinese students with English as a second language, and 7 native English-speaking students to identify the perception of the value of the intervention.

Australia's health care reform agenda: implications for the nurses' role in chronic heart failure management.

Introduction: The importance of the nursing role in chronic heart failure (CHF) management is increasingly recognised. With the recent release of the National Health and Hospitals Reform Commission (NHHRC) report in Australia, a review of nursing roles in CHF management is timely and appropriate.

Aim: This paper aims to discuss the implications of the NHHRC report and nursing roles in the context of CHF management in Australia.

Assessment of a self-administered adapted 6-minute walk test.

Purpose: This study assessed the reliability and viability of the Home-Heart-Walk (HHW) test, adapting a standardized 6-minute walk test protocol for self-administration.

Methods: Twenty-nine volunteers with documented coronary heart disease (CHD) undertook a structured 7-day program using the HHW.

Results: The intervention was well received by participants.

Chinese nurses' perceptions of heart health issues facing women in China: a focus group study.

Background: China is in a state of rapid economic growth and epidemiological transition. Morbidity and mortality relating to heart disease in women have increased dramatically.

Objectives: The aim of this study was to obtain the views of nurses regarding heart health issues for women in contemporary China.

Cardiovascular disease in Chinese women: an emerging high-risk population and implications for nursing practice.

Background: Globally, cardiovascular disease (CVD) is the leading cause of death among women. In China, the burden of CVD is increasing at an alarming rate; yet, it is underestimated and has important primary, secondary, and tertiary prevention issues.

Aim: This article seeks to document the issues surrounding the increased rate of CVD among Chinese women and describe the etiological factors and potential strategies to decrease the burden of disease.