Publications by authors named "Hugo W van Kessel"
Genome Biol
November 2024
Article Synopsis
- Tumours, especially in follicular lymphoma, show significant genetic and transcriptional diversity that influences cancer development and treatment strategies.
- The study introduces CaClust, an advanced model that combines various genomic data types to better understand tumor evolution and how genotypes translate into phenotypes.
- CaClust demonstrates improved performance over existing models and offers insights into mutations driving the disease, potential treatment targets, and confirms findings through single-cell analysis.
