Publications by authors named "Hugo R Jourde"

Article Synopsis
  • - Sleep spindles are brain oscillations that occur during sleep, and while they play a known role in memory consolidation, their effect on sleep continuity and memory protection is still being studied.
  • - One theory suggests that spindles act as a gate, preventing external sensory information from reaching the brain's cortex, while another theory claims that spindles don't suppress sound-related responses, even though they can occur in response to sounds.
  • - Research using EEG and MEG shows that auditory processing continues to some extent during sleep spindles and the brief refractory periods that follow them, providing new insights into how our brains manage sounds while we sleep.
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Closed-loop auditory stimulation (CLAS) is a brain modulation technique in which sounds are timed to enhance or disrupt endogenous neurophysiological events. CLAS of slow oscillation up-states in sleep is becoming a popular tool to study and enhance sleep's functions, as it increases slow oscillations, evokes sleep spindles and enhances memory consolidation of certain tasks. However, few studies have examined the specific neurophysiological mechanisms involved in CLAS, in part because of practical limitations to available tools.

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Closed-loop brain stimulation refers to capturing neurophysiological measures such as electroencephalography (EEG), quickly identifying neural events of interest, and producing auditory, magnetic or electrical stimulation so as to interact with brain processes precisely. It is a promising new method for fundamental neuroscience and perhaps for clinical applications such as restoring degraded memory function; however, existing tools are expensive, cumbersome, and offer limited experimental flexibility. In this article, we propose the Portiloop, a deep learning-based, portable and low-cost closed-loop stimulation system able to target specific brain oscillations.

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