Publications by authors named "Hugo N Pustilnik"
In Reply to the Letter to the Editor Regarding "Simultaneous Single-Trajectory Endoscopic Biopsy and Third Ventriculostomy in Pineal Region Tumors: A Systematic Review and Single Arm Meta-Analysis".
World Neurosurg
December 2024
Article Synopsis
- Robot-assisted techniques in stereotactic brain biopsies have improved safety and precision, making them a viable option for tissue diagnosis of intracranial lesions.
- A meta-analysis of 27 studies involving 2605 patients showed a high diagnostic yield of 98%, with a mean operative time of 52.45 minutes and a low risk of complications, including 6% for postoperative hemorrhage.
- Overall, the study indicates that robot-assisted biopsies offer significant advantages in terms of effectiveness and reduced complications, solidifying their role in the future of neurosurgical diagnostics.
Evaluating the efficacy and safety of flow diverter in pediatric cerebral aneurysm treatment: A systematic review and meta-analysis.
J Clin Neurosci
December 2024
Article Synopsis
- Intracranial aneurysms are rare in children, making up less than 5% of cases, and their unique shape poses challenges for treatment, particularly with the growing use of flow-diverter devices like the Pipeline Embolization Device (PED).
- A systematic review and meta-analysis were conducted using data from Medline, Embase, and Web of Science, focusing on studies with at least three pediatric patients to evaluate outcomes such as occlusion rates, complications, and mortality.
- The analysis included 80 patients and showed a high immediate occlusion rate of 90%, favorable clinical outcomes in 92% of cases, and a low complication rate of 3%, indicating that flow-diverter
Background: Barbed sutures eliminate knots and may offer some advantages over conventional sutures. This meta-analysis compares clinical, surgical, and economic outcomes of barbed sutures with standard closure techniques in spinal surgery.
Methods: We systematically searched PubMed, Embase, and Web of Science for studies comparing barbed and conventional suture for patients undergoing spinal surgery.
Background: Primary brainstem hemorrhage (PBSH) is a fatal condition related to hypertension. PBSH definitive treatment remains controversial, mainly when surgical options are discussed.
Objective: To aid decision-making in PBSH scenarios, we aimed to perform a meta-analysis and evaluate the literature on stereotactic aspiration (SA) for PBSH in comparison to conservative management (CM).
Chiari Malformation Type I (CMI) is a prevalent neurosurgical condition characterized by the descent of cerebellar tonsils below the foramen magnum. Surgery, aimed at reducing symptomatology and syrinx size, presents risks, making intraoperative neuromonitoring (IONM) a potentially vital tool. Despite its widespread use in cervical spine surgery, the utility of IONM in CMI surgery remains controversial, with concerns over increased operative time, cost, restricted anesthetic techniques and tongue lacerations.
View Article and Find Full Text PDFBackground And Objectives: Chronic subdural hematoma (CSDH) management involves various surgical techniques, with drainage systems playing a pivotal role. While passive drainage (PD) and active drainage (AD) are both used, their efficacy remains contentious. Some studies favor PD for lower recurrence rates, while others suggest AD superiority.
View Article and Find Full Text PDFBrain tissue oxygen plus intracranial pressure monitoring versus isolated intracranial pressure monitoring in patients with traumatic brain injury: an updated meta-analysis of randomized controlled trials.
Acta Neurochir (Wien)
May 2024
Background: Intracranial pressure (ICP) monitoring plays a key role in patients with traumatic brain injury (TBI), however, cerebral hypoxia can occur without intracranial hypertension. Aiming to improve neuroprotection in these patients, a possible alternative is the association of Brain Tissue Oxygen Pressure (PbtO2) monitoring, used to detect PbtO2 tension.
Method: We systematically searched PubMed, Embase and Cochrane Central for RCTs comparing combined PbtO2 + ICP monitoring with ICP monitoring alone in patients with severe or moderate TBI.
Background: Craniosynostosis, a developmental craniofacial anomaly, can impair brain development and cause abnormal skull shape due to premature closure of one or more cranial sutures. Traditional surgical treatments have evolved from open operations to minimally invasive endoscopic techniques. This systematic review and meta-analysis aim to evaluate the effectiveness and safety of the endoscopic approach in craniosynostosis correction.
View Article and Find Full Text PDFArticle Synopsis
- Meckel-Gruber Syndrome (MKS) is a severe genetic disorder characterized by occipital encephalocele, polycystic renal dysplasia, and postaxial polydactyly, leading to high mortality rates, often before or shortly after birth.
- A systematic review of the literature analyzed 10 cases of newborns with MKS who underwent surgical excision of encephaloceles, revealing complications and outcomes related to the procedure.
- Findings included an average gestational age of 36 weeks, common neurological issues like hydrocephalus, and a significant number of patients requiring post-surgical interventions such as mechanical ventilation, with pneumonia being a frequent cause of death.
Objective: To assess the efficacy and surgical outcomes of the simultaneous single-trajectory endoscopic biopsy and third ventriculostomy (ETV) in pineal region tumors.
Methods: A systematic review and meta-analysis adhering to Cochrane Standards and PRISMA framework were conducted. PubMed, Embase, and Web Of Science databases were searched until December 2023.
Background: The accurate etiological diagnosis of lower respiratory tract infections (LRTI) is essential for their effective clinical management. The extensive use of molecular methods during the COVID-19 pandemic has enabled massive data acquisition on viral lower respiratory tract infections. The current study aims to identify clinical features associated with eight viral agents among children presenting severe LRTI.
View Article and Find Full Text PDFIntroduction: The COVID-19 pandemic resulted in tremendous physical and psychological pressure on healthcare professionals, especially on those working in intensive care units (ICUs) and Emergency Departments (EDs). The present study intended to characterize the profile of these professionals which is associated with burnout and determine the potential predictors of such condition.
Methods: A Prospective cohort study was carried out in a tertiary hospital between March 2020 and March 2021, in Salvador, Brazil.