Systematic review of pharmacological management in Creutzfeldt-Jakob disease: no options so far?

Background: The Creutzfeldt-Jakob disease (CJD) is a spongiform encephalopathy that manifests as a rapidly progressive dementia syndrome. Currently, CJD has no cure, and many patients die within the first year, but some drugs are being studied as options for managing this condition.

Objective: To evaluate the effectiveness of pharmacological treatments offered to patients with CJD as a means to increase survival and reduce cognitive deterioration.

Treatment of chikungunya chronic arthritis: A systematic review.

Introduction: Chikungunya (CHIK) is a tropical arbovirus, transmitted by the female mosquito Aedes aegypti and Aedes albopictus. In Brazil, there have been cases reported since 2014. The initial manifestations of this virus are sudden onset high fever, headache, chills, rashes, myalgia and intense joint pain.

[Awareness about Aids among elderly males and young adults: a study of the perception of this disease].

The scope was to compare awareness of elderly males and young adults about aids, taking education into consideration. By means of an epidemiological, descriptive and cross-sectional study, the information of 30 elderly males and 62 young adults about the concept, transmission, prevention, diagnosis and treatment of aids was investigated by structured interviews based on a standardized and validated questionnaire. Frequency distribution, Chi-square test or Fisher's exact test, as well as Student's t test or the Mann-Whitney test were used, with a significance level of 0.