Split and Merge Watershed: a two-step method for cell segmentation in fluorescence microscopy images.

The development of advanced techniques in medical imaging has allowed scanning of the human body to microscopic levels, making research on cell behavior more complex and more in-depth. Recent studies have focused on cellular heterogeneity since cell-to-cell differences are always present in the cell population and this variability contains valuable information. However, identifying each cell is not an easy task because, in the images acquired from the microscope, there are clusters of cells that are touching one another.

Analysis of facial expressions in parkinson's disease through video-based automatic methods.

Background: The automatic analysis of facial expressions is an evolving field that finds several clinical applications. One of these applications is the study of facial bradykinesia in Parkinson's disease (PD), which is a major motor sign of this neurodegenerative illness. Facial bradykinesia consists in the reduction/loss of facial movements and emotional facial expressions called hypomimia.

CSMMI: class-specific maximization of mutual information for action and gesture recognition.

In this paper, we propose a novel approach called class-specific maximization of mutual information (CSMMI) using a submodular method, which aims at learning a compact and discriminative dictionary for each class. Unlike traditional dictionary-based algorithms, which typically learn a shared dictionary for all of the classes, we unify the intraclass and interclass mutual information (MI) into an single objective function to optimize class-specific dictionary. The objective function has two aims: 1) maximizing the MI between dictionary items within a specific class (intrinsic structure) and 2) minimizing the MI between the dictionary items in a given class and those of the other classes (extrinsic structure).

Acute leukemia classification by ensemble particle swarm model selection.

Objective: Acute leukemia is a malignant disease that affects a large proportion of the world population. Different types and subtypes of acute leukemia require different treatments. In order to assign the correct treatment, a physician must identify the leukemia type or subtype.