Post-LASIK Exophiala jeanselmei Keratitis.

Objective: To describe a patient diagnosed with Exophiala jeanselmei keratitis.

Methods: We report a case of a patient who developed infectious keratitis following laser in situ keratomileusis and chronic topical steroid use for approximately six months in both eyes. An atypical infiltrate containing dark pigmentation was noted in the left eye on the initial presentation.

The Ocular Microbiome Is Altered by Sampling Modality and Age.

Background: Studies of the ocular microbiome have used a variety of sampling techniques, but no study has directly compared different sampling methods applied to the same eyes to one another or to a reference standard of corneal epithelial biopsy. We addressed this lack by comparing the microbiome from three conjunctival swabs with those of corneal epithelial biopsy.

Methods: Twelve eyes (11 patients) were swabbed by calcium alginate swab, cotton-tipped applicator, and Weck-Cel cellulose sponge before a corneal epithelial biopsy (48 samples).

Role of in vivo confocal microscopy in the diagnosis of infectious keratitis.

Purpose: To investigate the utility of in vivo confocal microscopy (IVCM) in the diagnosis of infectious keratitis (IK).

Methods: Retrospective chart review of 46 patients with a final diagnosis of IK were included in the study. All patients received IVCM corneal imaging using the Heidelberg Retinal Tomography III system.

Correlation between Guttata Severity and Thickness of Descemet's Membrane and the Central Cornea.

: To characterize and correlate guttata severity, Descemet's membrane thickness (DMT), central cornea thickness (CCT) in corneas with guttae using specular microscopy and spectral-domain optical coherence tomography (SD-OCT) and test the Doheny Image Reading Center (DIRC) specular microscopy-based corneal guttata severity scale. : Forty-nine eyes of 49 patients with guttata and 36 eyes of age-matched of 36 normal controls were enrolled in the study. Three images of the central cornea and four of the peripheral cornea (inferior, superior, nasal and temporal) of each eye were taken using the Konan NSP-9900 specular microscope.

Reduction of Acanthamoeba Cyst Density Associated With Treatment Detected by In Vivo Confocal Microscopy in Acanthamoeba Keratitis.

Purpose: Acanthamoeba keratitis (AK) is a severe vision-threatening ocular infection that is frequently a diagnostic challenge. Treatment course is lengthy and often not fully effective. Contact lens wear has been recognized as the prime risk factor for AK.

Laboratory Results, Epidemiologic Features, and Outcome Analyses of Microbial Keratitis: A 15-Year Review From St. Louis.

Purpose: To evaluate the laboratory results and prognostic factors of poor clinical outcomes in microbial keratitis cases over 15 years at Saint Louis University.

Design: Retrospective cohort and trend study.

Methods: Microbiological and clinical information from culture-positive cases seen at Saint Louis University from 1999 to 2013 were reviewed retrospectively.

Evaluation of Corneal Epithelial Thickness Imaged by High Definition Optical Coherence Tomography in Healthy Eyes.

Purpose: To evaluate corneal epithelial thickness (CET) and corneal thickness (CT) in healthy eyes using spectral domain optical coherence tomography.

Methods: Thirty-six healthy eyes were imaged using the Cirrus high-definition (HD)-optical coherence tomography device. The average CET and CT were assessed using Cirrus Review Software within predefined concentric corneal ring-shaped zones.

Reproducibility of Central Corneal Thickness Measurements in Normal Eyes Using the Zeiss Cirrus 5000 HD-OCT and Pentacam HR.

Objectives: To determine the repeatability and reproducibility of Central Corneal Thickness (CCT) measurements using two different anterior segment imaging modalities, including those obtained with the new anterior segment lens attachments for the Cirrus 5000 HD-OCT.

Methods: A total of 32 eyes from 16 normal volunteers (8 male, 8 female) were enrolled in this prospective study. CCT was measured by the same examiner using the Cirrus 5000 HD-OCT and Pentacam HR.

Quantitative Analysis of Depth, Distribution, and Density of Cysts in Acanthamoeba Keratitis Using Confocal Microscopy.

Purpose: To quantify the density, distribution, and depth of invasion of cysts in the corneas of eyes with acanthamoeba keratitis (AK) by in vivo confocal microscopy (IVCM) with a novel scanning pattern.

Methods: The medical records of patients with AK evaluated at the Doheny Eye Center UCLA between September 2014 and July 2016 were reviewed retrospectively. Patients with clinically diagnosed AK underwent IVCM at various time points during their clinical course.

Indications for Keratoplasty at 3 Academic Centers from 2002 to 2012.

Objectives: To determine whether indications for keratoplasty differ between academic centers and the Eye Bank Association of America (EBAA) annual statistics from 2002 to 2012.

Methods: A retrospective review was performed for the indications for keratoplasty from 2002 to 2012 based on surgical specimens originating from three different academic centers. Data were compared with statistical reports obtained from the EBAA for the corresponding years.

Etiologies, Quantitative Hypoesthesia, and Clinical Outcomes of Neurotrophic Keratopathy.

Objectives: To report a series of patients with neurotrophic keratopathy and to correlate visual outcomes with the causative condition, grade of ulceration, and degree of cornea hypoesthesia.

Methods: A retrospective review of patients with neurotrophic keratopathy was conducted. The causality, visual acuities, ulcer grade, quantitative corneal sensitivity, treatments, and ocular comorbidities were recorded.

Assessment of risk factors for oxacillin-resistant ocular flora in eyes having cataract surgery.

Purpose: To assess the risk factors for eyes of cataract surgery patients harboring oxacillin-resistant Staphylococcus species on the ocular surface.

Setting: Ambulatory surgical center, Saint Louis University, Saint Louis, Missouri, USA.

Design: Prospective in vitro laboratory study of a patient cohort.

Microbial keratitis in los angeles: the doheny eye institute and the los angeles county hospital experience.

Objective: To evaluate the spectrum and antibiotic susceptibility panel of infectious keratitis at a major tertiary care referral eye center and a major county hospital in Southern California.

Design: Retrospective case series.

Participants: All cultured infectious keratitis cases from July 1, 2008, through December 31, 2012, from the Doheny Eye Institute (DEI) and the Los Angeles County + University of Southern California Medical Center (LAC+USC) were evaluated.

Surgical management of non-traumatic pediatric ectopia lentis: A case series and review of the literature.

Purpose: To report a small series of pediatric patients with ectopia lentis that underwent limbal-approach lensectomy and vitrectomy and scleral-fixated intraocular lens implantation and to review the literature on the topic of surgical management of ectopia lentis.

Method: A retrospective review of 13 eyes of seven patients that underwent lensectomy, vitrectomy, and scleral-fixated intraocular lens implantation and a review of the ophthalmic literature.

Results: In our series, the average age at surgery was 70.

Two-year outcomes of an initial series of DSAEK cases in normal and abnormal eyes at an inner-city university practice.

Purpose: To report our initial series of Descemet stripping automated endothelial keratoplasty (DSAEK) patients with 2 years of follow-up and to compare the complications and outcomes between normal and abnormal eyes.

Methods: Records of all patients who underwent DSAEK between April 2007 and April 2009 were reviewed. Eyes were categorized as "normal" or "abnormal" for comparison.

Ocular flora and their antibiotic resistance patterns in the midwest: a prospective study of patients undergoing cataract surgery.

Purpose: To determine the spectrum of conjunctival flora and the antibiotic susceptibility profiles of patients undergoing cataract surgery at a Midwestern university.

Design: Prospective in vitro laboratory investigation of a patient cohort.

Methods: Conjunctival cultures were obtained from patients undergoing cataract surgery at a single ambulatory center on the day of surgery before the instillation of any ophthalmic medications.

Resistant Fusarium keratitis progressing to endophthalmitis.

Objective: To report a case of multidrug-resistant Fusarium sp keratitis that progressed to endophthalmitis and that eventually required enucleation.

Methods: Case report and literature review. Isolate identification and susceptibility testing were performed by the Fungus Testing Laboratory at San Antonio, TX.

Keratoconus association with axial myopia: a prospective biometric study.

Objectives: To determine if the axial length and its components are significantly different between a keratoconic eye and an emmetropic eye and also to determine if the degree of corneal ectasia is associated with axial myopia in a keratoconic eye.

Methods: A prospective observational study was conducted with keratoconic patients and emmetropic controls. All subjects underwent corneal topography analysis and axial length measurement by immersion-ultrasound biometry.

Community opinions in the management of corneal ulcers and ophthalmic antibiotics: a survey of 4 states.

Objective: To evaluate the ophthalmic community's current opinions of the management of bacterial keratitis and usage of the currently available ophthalmic antibiotics.

Methods: An anonymous questionnaire was mailed to ophthalmologists in California, Florida, Illinois, and Missouri. The results were tabulated and analyzed statistically.

Nondisplacement of descemet stripping automated endothelial keratoplasty lenticule after traumatic rupture of the globe.

Purpose: The purpose of this study was to report a case of nondisplacement of an endothelial keratoplasty (EK) lenticule after traumatic rupture of the globe.

Methods: The authors conducted a review of the clinical course of a 35-year-old woman who sustained a traumatic rupture of the globe 4 months after Descemet stripping endothelial keratoplasty.

Results: The rupture did not involve the 4-month-old temporal scleral tunnel wound used for the EK.

Distinct central representations for sensory fibers innervating either the conjunctiva or cornea of the rat.

The laminar sheet of epithelium (e.g., skin and mucous membrane) enclosing our bodies is represented in the dorsal horns of the medulla and spinal cord.