Publications by authors named "Hugo Borsetti"
Article Synopsis
- An outbreak of mange caused by Psoroptes sp. was identified in a llama herd in Jujuy province, Argentina, with symptoms including hair loss, skin inflammation, and ear drainage.
- Microscopic analysis confirmed the presence of Psoroptes mites, and histological studies indicated an allergic reaction with mixed inflammatory cells.
- The research also revealed genetic links between local llama infections and similar infections in rabbits and bighorn sheep, emphasizing the need for further studies to manage these parasitic issues in South American camelids.
A high-throughput cell-based screen identified redox-active small molecules that produce a period lengthening of the circadian rhythm. The strongest period lengthening phenotype was induced by a phenazine carboxamide (VU661). Comparison to two isomeric benzquinoline carboxamides (VU673 and VU164) shows the activity is associated with the redox modulating phenazine functionality.
View Article and Find Full Text PDFBackground: Daily cycles of sleep/wake, hormones, and physiological processes are often misaligned with behavioral patterns during shift work, leading to an increased risk of developing cardiovascular/metabolic/gastrointestinal disorders, some types of cancer, and mental disorders including depression and anxiety. It is unclear how sleep timing, chronotype, and circadian clock gene variation contribute to adaptation to shift work.
Methods: Newly defined sleep strategies, chronotype, and genotype for polymorphisms in circadian clock genes were assessed in 388 hospital day- and night-shift nurses.