Publications by authors named "Hugo Alejandro Jimenez-Vazquez"
Article Synopsis
- Anticonvulsants, particularly voltage-dependent sodium channel blockers (VGSCB), are crucial for treating seizures and work by affecting brain activity and inhibition.
- The study focused on identifying the structural features that enhance the effectiveness of VGSC blockers using quantitative structure-activity relationship analysis.
- Results indicated that greater polarity, basicity, and specific structural characteristics, such as urea derivatives and aromatic substitutions, significantly improve the biological activity of these drugs.
