Effect of submucosal dexamethasone on postoperative pain, swelling and trismus after periodontal surgery: a randomized clinical study.

Objective: The aim of this study is to evaluate the effectiveness of submucosal 8 mg (2 mL) dexamethasone (DEX) on postoperative pain, swelling, chewing efficiency, trismus, healing, and discomfort after periodontal flap surgery (PFS).

Methods: In this randomized controlled split-mouth study, 25 patients underwent PFS in the mandible, whereby postoperative, submucosal DEX was injected to the surgical field to the test group and submucosal normal saline was applied to the control group. Pain was evaluated using the Visual Analogue Scale (VAS) and the 101-point numeric rate scale in the first 8 h after PFS and on the 2nd, 3rd, 4th, and 7th days, whereas swelling, chewing efficiency, trismus, healing, discomfort and analgesic consumption were evaluated preoperatively on the 1st, 2nd and 7th days.

Growth Dynamic of the Dorsum Sellae in Fetuses.

Objective: To determine the dimension of the dorsum sellae (DS) in fetuses.

Methods: Skull bases of 32 fetuses aged from 17 to 32 weeks were included in the work. The length of the DS at its superior border (DSL-SB) and the thickness of DS at its middle part (DST-ML) were measured.

Sphenoid Ridge in Fetuses: Size Analysis, Classification, and Clinical Implications.

Objective: To identify the size and angle of the sphenoid ridge (SR) in fetuses.

Methods: Skull bases of 32 fetuses (11 males / 21 females) aged 17 to 32 weeks of gestations were included the study. The angle of SR (SRA), length of LW (SRL), and also LW widths at the midline (SRW-ML), at the midpoint (SRW-MP), and at the lateral point (SRW-L) were measured.

Muscle inflammation is regulated by NF-κB from multiple cells to control distinct states of wasting in cancer cachexia.

Although cancer cachexia is classically characterized as a systemic inflammatory disorder, emerging evidence indicates that weight loss also associates with local tissue inflammation. We queried the regulation of this inflammation and its causality to cachexia by exploring skeletal muscle, whose atrophy strongly associates with poor outcomes. Using multiple mouse models and patient samples, we show that cachectic muscle is marked by enhanced innate immunity.

Crista Galli Morphology in Fetuses.

Objective: To determine alterations in the crista galli (CG) size in fetuses with advancing weeks.

Methods: Skull bases of 32 fetuses (11 males/21 females) aged 17 to 32 weeks in utero were included in the study. The width (width of CG), height (height of CG), and length (length of CG) of CG were measured, and also olfactory fossa depth (OFD) was measured to determine the relation of CG with OFD.

Posterior clinoid process in children: morphometric analysis, pneumatization ratio, and surgical implications.

Purpose: To describe pneumatization and topographic position of the posterior clinoid process (PCP) in healthy children when approaching the anterior and middle fossae.

Methods: The study consisted of computed tomography images of 180 pediatric patients (90 males / 90 females), aged 1-18 years. The presence or absence of PCP pneumatization was noted, and the distances of certain landmarks to PCP were measured.

Removal of manganese (Mn) from water samples using a biocomposite sorbent.

Herein, tannic acid-tethered cellulose was developed as an efficient and selective sorbent for Mn⁺ removal from aqueous solutions. The modified cellulose was characterized through scanning electron microscopy, infrared spectroscopy, and elemental analyses. Sorption performance was evaluated using various parameters, including pH, initial Mn⁺ concentration, contact time, and the presence of interfering ions.

The effect of erector spinae plane block on postoperative extubation time and laboratory parameters in open heart surgery: a retrospective study.

Background/aim: In open heart surgery, sternotomy causes inflammation in tissues, and inflammation causes postoperative pain. This study aims to examine the effects of bilateral erector spinae plane (ESP) blocks on postoperative extubation time and laboratory parameters in open heart surgery.

Materials And Methods: The study was managed using retrospective data from 85 patients who underwent open-heart surgery.

Improving Cleaning Efficiency through the Measurement of Food Fouling Adhesive Strength.

This study aims to investigate the impacts of factors, including textural properties, surface roughness, and contact angle, on the cleaning performance of food soils and develop a preliminary mathematical model to predict the cleaning score, depending on the soil-surface properties. The force required to remove soil from the surface was determined by a texture analyzer equipped with a newly designed probe. Potato puree and egg yolk soils showed high adhesive forces compared to other deposits.

Radiologic evaluation of the Vidian canal in the pediatric population.

Purpose: This examination aimed to display the size and topographic position of the Vidian canal (VC) in normal children.

Methods: 180 pediatric subjects aged 1-18 years were included this computed tomography examination. The distances of VC to certain landmarks, and VC length were measured.

Are deep learning classification results obtained on CT scans fair and interpretable?

Following the great success of various deep learning methods in image and object classification, the biomedical image processing society is also overwhelmed with their applications to various automatic diagnosis cases. Unfortunately, most of the deep learning-based classification attempts in the literature solely focus on the aim of extreme accuracy scores, without considering interpretability, or patient-wise separation of training and test data. For example, most lung nodule classification papers using deep learning randomly shuffle data and split it into training, validation, and test sets, causing certain images from the Computed Tomography (CT) scan of a person to be in the training set, while other images of the same person to be in the validation or testing image sets.

Rapid initiation of antiretroviral therapy in Turkey: a modeling study.

Background: To effectively control the HIV epidemic and meet global targets, policymakers recommend the rapid initiation of antiretroviral therapy (ART). Our study aims to investigate the effect of rapid ART programs on individuals diagnosed with HIV, considering varying coverage and initiation days after diagnosis, and compare it to standard-of-care ART treatment in Turkey.

Methods: We used a dynamic compartmental model to simulate the dynamics of HIV infection in Turkey.

Clinical importance of serum miRNA levels in breast cancer patients.

There is limited data on the relationship of miRNAs with parameters that may affect surgical management or reflect tumour prognosis. It was aimed to evaluate serum miRNA levels in breast carcinoma cases and reveal the relationship between these levels and prognosis-related factors such as the histological type of the tumour, estrogen receptor, progesterone receptor, Ki-67 index, HER-2neu, E-cadherin, tumour size, CK5/6, CA15.3 levels, number of tumour foci, number of metastatic lymph nodes, and status of receiving neoadjuvant therapy.

CAP-RNAseq: an integrated pipeline for functional annotation and prioritization of co-expression clusters.

Cluster analysis is one of the most widely used exploratory methods for visualization and grouping of gene expression patterns across multiple samples or treatment groups. Although several existing online tools can annotate clusters with functional terms, there is no all-in-one webserver to effectively prioritize genes/clusters using gene essentiality as well as congruency of mRNA-protein expression. Hence, we developed CAP-RNAseq that makes possible (1) upload and clustering of bulk RNA-seq data followed by identification, annotation and network visualization of all or selected clusters; and (2) prioritization using DepMap gene essentiality and/or dependency scores as well as the degree of correlation between mRNA and protein levels of genes within an expression cluster.

The effect of structured supportive approach based on Kolcaba's comfort theory applied to parents of children with cerebral palsy on child's comfort, quality of life, and parent's self-efficacy: A randomised controlled trial.

Aim: This study aims to assess how a structured supportive approach applied to the parents of children living with cerebral palsy according to how the Theory of Comfort affects the child's comfort, quality of life, and parent's self-efficacy.

Design: A single-blind, randomised, controlled experimental trial.

Methods: The study was conducted with parents of children with cerebral palsy aged between 8 and 16 years who presented to the rehabilitation centers between October 2021 and November 2022.

The effect of online peer and adult education given to adolescents with allergic asthma on their quality of life, self-efficacy, anxiety, and disease knowledge and management: a randomized controlled study.

Objective: To examine the effect of interactive online education given by peers or adults on anxiety, self-efficacy, quality of life, disease knowledge and management in adolescents with allergic asthma.

Methods: This was a randomized controlled trial. The study sample consisted of 84 adolescents divided into experimental groups (peer education group, adult education group) and a control group.

Production of Ultrafine PVDF Nanofiber-/Nanonet-Based Air Filters via the Electroblowing Technique by Employing PEG as a Pore-Forming Agent.

Particles with diameters smaller than 2.5 μm (PM) can penetrate the respiratory system and have negative impacts on human health. Filter media with a porous surface and nanofiber/nanonet structure demonstrate superior filtration performance compared to traditional nano- and microfiber-based filters.

Modeling the future of HIV in Turkey: Cost-effectiveness analysis of improving testing and diagnosis.

Aims: This study aimed to determine HIV incidence and prevalence in Turkey and to estimate the cost-effectiveness of improving testing and diagnosis in the next 20 years.

Background: HIV incidence in Turkey has been rapidly increasing in the last decade with a particularly high rate of infection for younger populations, which underscores the urgent need for a robust prevention program and improved testing capacity for HIV.

Methods: We developed a dynamic compartmental model of HIV transmission and progression among the Turkish population aged 15-64 and assessed the effect of improving testing and diagnosis.

Multi-drug resistant Klebsiella-induced corneal ulcer following pterygium surgery: a case report.

Background: Management of pterygium is dependent on the grading of pterygium and its clinical presentation (inflamed or quiescent), and surgical excision is the final choice of treatment for the pterygium extending beyond the limbus. Infectious keratitis is one of the most commonly reported complications in recent years. To the best of our knowledge, Klebsiella keratitis after pterygium surgery has not been described in the current literature.

Effects of litter size and caging on physical and mental development in rats.

As a multidisciplinary field, laboratory animal science promotes or accelerates the emergence of innovative ideas and products. As research has increased, so has the demand for laboratory animals with reliable, standardized characteristics. Thus, the breeding, reproduction, and welfare of laboratory animals are now animals reliable and more.

Evaluation of the effectiveness of diode laser therapy in conjunction with nonsurgical treatment of peri-implantitis.

Purpose: Peri-implantitis (PI) is an inflammatory condition associated with the destruction of bone tissue around a dental implant, and diode lasers can be used to treat this disease. In this study, we aimed to evaluate the effectiveness of a 940-nm diode laser for the nonsurgical treatment of PI.

Methods: Twenty patients (8 women and 12 men) were enrolled in a split-mouth randomized controlled study.