Practical implementation of automated insulin delivery systems in 2025: A French position statement update.

The advent of automated insulin delivery (AID) systems in 2020 marked a disruptive event in managing type 1 diabetes, benefiting children and adults alike. By 2024, advances in real-world data and research motivated an update to the French consensus on AID systems to expand accessibility, refine guidelines, and optimize patient follow-up. AID systems have consistently improved glycemic control by reducing HbA1c, increasing time-in-range (TIR), and minimizing hypoglycemia, with significant benefits even for specific populations such as individuals with poor glycemic control, brittle diabetes, children, very young children, pregnant women, those with insulin resistance or gastroparesis, or after bariatric surgery.

A step towards efficient water splitting: a high-performance CuCo(OH)/CNT/MoS electrocatalyst.

A high-performance CuCo(OH)/CNT/MoS composite electrocatalyst was synthesized by rapid co-precipitation. This bifunctional material exhibits exceptional electrochemical properties, achieving low overpotentials of 65 mV (OER) and 211 mV (HER) at , with Tafel slopes of 96 mV dec and 110 mV dec. Notably, CuCo(OH)/CNT/MoS demonstrates remarkable durability, sustaining its activity for more than 40 hours in alkaline and 25 hours in acidic media, accompanied by minimal charge transfer resistance.

Epidermodysplasia Verruciformis: A Case Series.

Epidermodysplasia verruciformis (EV) is an uncommon disease that is inherited autosomal recessively. It has a heightened vulnerability to human papillomavirus (HPV) infection, which manifests as hyperpigmented or hypopigmented macular lesions, lesions resembling pityriasis versicolor (PV) and planar warts, and an increased risk of progressing to skin cancer, especially in sun-exposed areas. We report three cases of EV with varying presentations.

A New Approach to Synthesizing Carbon-11-PBR28 and its Clinical Validation in ALS Patients.

Background: Many studies have reported Translocator Protein (TSPO) overexpression in many neurological disorders. Carbon-11[11C]PBR28 is a widely used TSPO Positron Emission Tomography (PET) radiopharmaceutical. We have compared HPLC-based purification with cartridge-based purification and performed PET-MR imaging in ALS patients.

Evaluation of the iodoacetic acid effects on adipose-derived mesenchymal stem cells and alteration of their osteogenic differentiation potential by inducing oxidative stress.

Drinking water disinfection byproducts (DBPs) can adversely affect human health. Iodoacetic acid (IAA) is a DBP associated with most cytotoxic, genotoxic, and mutagenic disorders. However, its effects on the osteogenic differentiation of adipose-derived mesenchymal stem cells, ADMSCs, remain unknown.

Melatonin-governed growth and metabolome divergence: Circadian and stress responses in key plant species.

Melatonin, a versatile biomolecule, profoundly influences plant growth and resilience through its intricate regulation of metabolic pathways, circadian rhythms, and cellular processes. The current study elucidates melatonin's concentration-dependent biphasic effects on growth dynamics in Arabidopsis thaliana and Brassica nigra. While 50 μM melatonin optimized biomass accumulation and root elongation, higher concentrations (100 μM) elicited stress responses, underscoring its dual role as a growth promoter and stress modulator.

Comparison of Scapulohumeral rhythm in individuals with and without Forward Shoulder Posture.

Background: Forward Shoulder Posture (FSP) is one of the most common postural deviations of the upper back, which may affect the scapulohumeral rhythm (SHR). This study aimed to investigate changes in scapulohumeral rhythm during scapular plane shoulder abduction between individuals with and without FSP.

Methods: A cross sectional study with two group comparison.

Automated classification of mandibular canal in relation to third molar using CBCT images.

Background: Dental radiology has significantly benefited from cone-beam computed tomography (CBCT) because of its compact size and low radiation exposure. Canal tracking is an important application of CBCT for determining the relationship between the inferior alveolar nerve and third molar. Usually, canal tacking is performed manually, which takes a lot of time.

Surgically assisted maxillary expansion: Influence of piezosurgery on the complications linked to the midline osteotomy.

Transverse maxillary deficiency requires surgical maxillary expansion when the midpalatal suture is closed. The midline osteotomy of the maxilla can lead to significant dental, gingival and bone complications. Technically, this osteotomy is usually performed using osteotomes, a burr or an oscillating saw, but is increasingly being replaced by piezosurgery.

Exploring the role of the JEEViKA swasthya mitra helpdesk in improving healthcare access: a qualitative study in tertiary healthcare facilities in Bihar, India.

Background: Rural populations in Bihar, India, face significant healthcare access challenges due to geographical, infrastructural, and financial barriers. The Swasthya Mitra program, initiated by the Bihar Rural Livelihood Promotion Society in collaboration with local and international partners, aims to mitigate these challenges by employing trained community members to navigate patients through the healthcare system.

Methods: This qualitative study employed in-depth interview and thematic analysis to evaluate the Swasthya Mitra program in the Bhagalpur and Jamui districts in Bihar, India.

Romiplostim Reduces Platelet Transfusion Needs in Multiple Myeloma Patients Undergoing Autologous Stem Cell Transplantation.

Background: There is no standard treatment to accelerate recovery from melphalan-induced thrombocytopenia in multiple myeloma (MM) patients undergoing autologous stem cell transplantation (ASCT). Romiplostim, a thrombopoietin receptor agonist, has been developed to upregulate platelet production.

Objective: This study aimed to assess the efficacy and safety of romiplostim in reducing platelet transfusions post-ASCT in MM patients.

What happens when you turn weed management off? A long-term appraisal of the effectiveness of Pteridium aquilinum (L.) kuhn control treatments and the role of sheep grazing.

Long-term strategies are needed for the ecological restoration of land invaded by perennial weed species comprising of two parts: (1) control of the invasive species and (2) restoration of native vegetation meeting agricultural/conservation objectives. We investigated this within a statistically-rigorous, 28-year experiment at a site where Pteridium aquilinum had invaded an acid-grass/heathland. Where P.

Longer term follow-up of abdominal symptoms (CFAbd-Score) after initiation of Elexacaftor / Tezacaftor / Ivacaftor in adults with cystic fibrosis.

Background: Whether improvements in gastrointestinal (GI) symptoms observed with Elexacaftor/Tezacaftor/Ivacaftor (ETI) treatment are sustained in the longer-term requires exploration. This study investigated how GI-symptoms change with longer-term ETI use in pancreatic insufficient adults with cystic fibrosis (awCF).

Methods: Participants completed up to three abdominal symptom questionnaires, employing the validated CFAbd-Score.

STAT3-related lncRNAs in colorectal cancer progression; Special focus on immune cell's evasion.

Colorectal cancer (CRC) is globally ranked as the third leading cause of cancer-related deaths in both men and women. There is an urgent need for novel biomarkers to facilitate early diagnosis and enhance patient care, thereby improving treatment response and reducing mortality rates. Signal transducer and activator of transcription 3 (STAT3) is essential for controlling the anti-tumor immune response since it is a hub for several oncogenic signaling pathways.

Traumatic Neuroma as a Rare Complication of "Vel" Piercing.

Body piercing has become popular among people of all ages, inspired by religious convictions, personal aesthetics, and cultural influences. Piercings in the oral cavity frequently involve the lip, buccal mucosa, frenulum, and tongue with needles, hooks, and rings. However, these piercings might cause long-term problems to both the hard and soft tissues of the mouth.

R(3780) Resonance Interpreted as the 1^{3}D_{1}-Wave Dominant State of Charmonium from Precise Measurements of the Cross Section of e^{+}e^{-}→Hadrons.

We report the precise measurements of the cross section of e^{+}e^{-}→hadrons at center-of-mass energies from 3.645 to 3.871 GeV.

A new species and a new record of Aulacus Jurine (Hymenoptera, Aulacidae) from the North Andean block with a key to Colombian species.

A new species of Aulacus Jurine from the Colombian Andes, A. gracielae Santos & Mazariegos sp. nov.

Navigating the Diagnostic Labyrinth of Scrofuloderma Orbit in Conjunction with Jungling's Disease.

Tuberculosis (TB) manifests in various forms, including extrapulmonary tuberculosis (EPTB), which poses diagnostic dilemmas due to its wide-ranging clinical presentations. When TB affects the bones of the hands and feet, it can present a diagnostic labyrinth for clinicians. In such cases, the differential diagnosis may include Jungling's bone disease, adding complexity to the diagnostic process.

Total Elbow Replacement in Swine: Surgical Technique and Initial Clinical Experience in a Kunekune Sow.

Objective:  The aim of this study was to describe the development of a total elbow replacement (TER) technique in swine and report the outcome of TER in a Kunekune sow (61 kg) with severe elbow osteoarthritis.

Methods:  The technique was developed by operating on three pig cadavers (Yorkshire 40-50 kg). The TATE Elbow implant fit was confirmed with modeling to the patient's computed tomography imaging.

XIII Consenso SIBEN sobre Traslado Neonatal: Establecer protocolos estructurados para el proceso del traslado neonatal podría mejorar los desenlaces.

La centralización de los partos de alto riesgo en los hospitales con el más alto nivel de atención es fundamental para ampliar el margen de seguridad materno-neonatal y mejorar los desenlaces. Por lo tanto, es altamente recomendable trasladar oportunamente a las pacientes gestantes portadoras de embarazos de alto riesgo y/o con amenazas de parto pretérmino a centros de atención terciaria, sin embargo, no siempre es posible anticipar los riesgos antenatalmente, lo cual resulta en la necesidad de trasladar a neonatos en estado crítico. Lamentablemente, la movilización de los recién nacidos compromete aún más su estado de salud, especialmente en los países latinoamericanos.

M, NM-polynomials Based on Reverse, Reduced Reverse Degree and Neighborhood Degree Based Topological Indices with Applications to Bond Energy of Y-Junction Nanotubes.

Background: In graph theory, M polynomials like the matching polynomial are very crucial in examining the matching structures within graphs, while NM polynomials extends this to analyze non-matching edges. These polynomials are important in many fields, including chemistry and network architecture. They support the derivation of topological indices for protein structure analysis, network communication optimization, and drug design in QSAR/QSPR investigations.

Mechanical, fatigue and super plasticity properties of Cu-Al-Mn, Cu-Al-Be-Mn shape memory alloy and their metal matrix composites.

This study explores the characteristics and potential engineering applications of Cu-Al-Mn and Cu-Al-Be-Mn shape memory alloys (SMAs). The research investigates the chemical composition, transformation temperatures, and mechanical properties of these SMAs when incorporated into Al metal matrix composites (MMCs). It was found that the addition of Mn and Be, has a significant impact on the performance of Cu-Al alloys.

A rare case report: The value of fetal MRI to detect diprosopus twins.

Diprosopus is one of the rarest types of conjoined twins, caused by incomplete zygote separation in early pregnancy. It defines a condition with duplication of facial structures, monocephalic and 1 trunk. Early detection is difficult, but fetal MRI plays an important role in strengthening antenatal diagnosis of conjoined twin pregnancies and other major congenital abnormalities, complementing antenatal ultrasonography.