The Estrogen-Immune Interface in Endometriosis.

Endometriosis is a gynecologic condition characterized by the growth of endometrium-like stroma and glandular elements outside of the uterine cavity. The involvement of hormonal dysregulation, specifically estrogen, is well established in the initiation, progression, and maintenance of the condition. Evidence also highlights the association between endometriosis and altered immune states.

Mobile Robot Positioning with Wireless Fidelity Fingerprinting and Explainable Artificial Intelligence.

Wireless Fidelity (Wi-Fi) based positioning has gained popularity for accurate indoor robot positioning in indoor navigation. In daily life, it is a low-cost solution because Wi-Fi infrastructure is already installed in many indoor areas. In addition, unlike the Global Navigation Satellite System (GNSS), Wi-Fi is more suitable for use indoors because signal blocking, attenuation, and reflection restrictions create a unique pattern in places with many Wi-Fi transmitters, and more precise positioning can be performed than GNSS.

Robot-Assisted Laparoscopic Application of Fibrin Sealant Patch for Repair of Inferior Vena Cava.

Introduction: There is a risk of iatrogenic vascular injuries during robotic-assisted laparoscopic excision of diaphragmatic endometriosis. Although studies are limited, the first reported case of a suprahepatic inferior vena cava (IVC) injury during robotic diaphragmatic endometriosis excision was successfully treated using a fibrin sealant patch, preventing exsanguination and conversion to laparotomy.

Case Description: A 36-year-old female with a history of recurrent catamenial pneumothorax and two prior video-assisted thoracoscopic surgeries to treat diaphragmatic endometriosis presented to our clinic with right-sided shoulder pain and a chest tube in place.

Descriptive qualitative study of breathlessness and its management of Turkish individuals with self-reported heart failure.

Aims: To explore the experiences of individuals with heart failure, with a specific focus on elucidating the full spectrum of symptoms experienced and their subjective descriptions of breathlessness and self-management strategies regarding socio-cultural-behavioural context.

Design: Qualitative descriptive study underpinned by critical realism and situation-specific theory of heart failure self-care.

Setting: Participants from various settings (hospitals and community) in Southeastern Türkiye.

Long-Range Self-Hybridized Exciton-Polaritons in Two-Dimensional Ruddlesden-Popper Perovskites.

Lead halide perovskites have emerged as platforms for exciton-polaritonic studies at room temperature, thanks to their excellent photoluminescence efficiency and synthetic versatility. In this work, we find proof of strong exciton-photon coupling in cavities formed by the layered crystals themselves, a phenomenon known as the self-hybridization effect. We use multilayers of high-quality Ruddlesden-Popper perovskites in their 2D crystalline form, benefiting from their quantum-well excitonic resonances and the strong Fabry-Pérot cavity modes resulting from the total internal reflection at their smooth surfaces.

Beyond Index Conditions: Applying a Multimorbidity Approach to Renal Cancer Nursing.

Objective: This article aims to describe the key components of renal cancer nursing and multimorbidity nursing, and reflects on how adopting a multimorbidity approach to renal cancer nursing can help nurses provide holistic patient care.

Methods: This is a discussion paper drawing on relevant evidence and theory.

Results: Renal cancer nurses have a highly specialised knowledge base and are able to use this expertise to deliver excellent care to people with cancer.

A plasmonic biosensor pre-diagnostic tool for Familial Mediterranean Fever.

Familial Mediterranean Fever (FMF) is an autosomal recessive genetic disorder, primarily observed in populations around the Mediterranean Sea, linked to MEFV gene mutations. These mutations disrupt inflammatory responses, increasing pyrin-protein production. Traditional diagnosis relies on clinical symptoms, family history, acute phase reactants, and excluding similar syndromes with MEFV testing, which is expensive and often inconclusive due to heterozygous mutations.

Sinonasal Anatomic Variations in the Adult Population: CT Examination of 1200 Patients.

Background: The nasal cavity and paranasal sinuses are one of the most frequently anatomically varied regions. Their size and shape vary from person to person, and ethnic origin may have a role in this variety. Recognizing this variations is so important for ear nose throat (ENT) specialists because they predispose to sinonasal pathologies and affect the complication rate and success of endoscopic sinus surgery.

Obesogenic Medication Use in End-Stage Kidney Disease and Association With Transplant Listing.

Objectives: Obesogenic medications are a putative contributor to the obesity epidemic. While 20% of adults take ≥1 obesogenic medication, the proportion in the end-stage kidney disease (ESKD) population-a group enriched for cardiometabolic complications-is unknown. Obesogenic medications may contribute to obesity and hamper weight loss efforts to achieve transplant listing.

Rare Broad Ligament Cavernous Hemangioma Mimicking Advanced Endometriosis: A Case Report.

Cavernous hemangioma within the female genital tract is an extremely rare pathology, characterized by irregular vascular spaces containing blood or thrombus. We present a unique case of a 42-year-old primiparous woman who presented with typical endometriosis symptoms such as dysmenorrhea, dyspareunia, and heavy menstrual bleeding. The patient also experienced complex postpartum symptoms, which were misdiagnosed as cholecystitis and retained placental products.

Peanut shell biochar for Rhodamine B removal: Efficiency, desorption, and reusability.

A high-performance and affordable peanut shell-derived biochar was employed for the efficient removal of Rhodamine B (RhB) from aqueous solutions. The properties of peanut shell biochar (PSB) were investigated through Fourier transform infrared (FTIR) spectroscopy and Brunauer-Emmett-Teller surface area measurements. The FTIR analysis revealed numerous active sites and functional groups for the binding of dye molecules, while the BET surface area was determined to be 351.

Relationship between response to first-line steroid treatment in adult immune thrombocytopenic purpura and the course of the disease.

Background: Immune thrombocytopenic purpura, a recurrent autoimmune disease, is characterized by thrombocytopenia, purpura and hemorrhagic episodes with the main factor in the pathogenesis of this disease being autoantibodies against platelets. Since the 1950s, first-line treatment has been glucocorticoids that have indirect and direct effects on thrombocytopenia. Although the characteristics associated with the chronicization of immune thrombocytopenic purpura at the time of diagnosis have been investigated in previous studies, no study was found in the literature investigating the relationship between the response to first-line steroid treatment and the course of the disease, the aim of this study.

Assessment of serum granulysin and cathepsin-L levels in vitiligo patients.

Objective: Cellular and humoral immunity plays a role in the pathogenesis of vitiligo. T lymphocytes and natural killer cells involved in cellular immunity carry out their cytotoxic activities through perforin/granzyme-dependent granule exocytosis, in which granulysin and cathepsin-L are also involved. The aim of this study was to investigate the possible role of serum granulysin and cathepsin-L in the etiopathogenesis of vitiligo and their association with disease activity and severity.

Quantifying cognitive and affective impacts of Quizlet on learning outcomes: a systematic review and comprehensive meta-analysis.

Background: This study synthesizes research on the impact of Quizlet on learners' vocabulary learning achievement, retention, and attitude. Quizlet's implementation in language education is posited to enhance the learning experience by facilitating the efficient and engaging assimilation of new linguistic concepts. The study aims to determine the extent to which Quizlet influences vocabulary learning achievement, retention, and attitude.

Can urinary caspase-3 and cytochrome c levels be used as predictive biomarkers in the management of unilateral antenatal hydronephrosis?

Purpose: We aimed to investigate the urinary caspase-3 and cytochrome c levels in patients with unilateral antenatal hydronephrosis and to determine whether changes in urinary biomarker levels could be useful for both predicting the need for surgical intervention due to ureteropelvic junction obstruction (UPJO) and postoperative surgical success.

Methods: Sixty-five children with a history of unilateral antenatal hydronephrosis and postnatal anteroposterior diameter ≥ 10 mm were included in this prospective case-control study between January 2013 and December 2021. The obstruction group consisted of 33 patients (28 boys, 84.

Cumulative incidence and risk factors for cutaneous squamous cell carcinoma metastases in organ transplant recipients: The Skin Care in Organ Transplant Patients in Europe-International Transplant Skin Cancer Collaborative metastases study, a prospective multicenter study.

Introduction: Solid organ transplant recipients (SOTRs) are believed to have an increased risk of metastatic cutaneous squamous cell carcinoma (cSCC), but reliable data are lacking regarding the precise incidence and associated risk factors.

Methods: In a prospective cohort study, including 19 specialist dermatology outpatient clinics in 15 countries, patient and tumor characteristics were collected using standardized questionnaires when SOTRs presented with a new cSCC. After a minimum of 2 years of follow-up, relevant data for all SOTRs were collected.

Bariatric Surgery and Weight Gain: Bibliometric Analysis.

Purpose: Bariatric surgery is the most successful method for weight loss; however, weight regain may occur in the long term. It depends on eating habits and self-management. The study aimed to conduct a bibliometric analysis on bariatric surgery and weight gain and to determine the content and trends in the literature.

In vitro effects of heparin-binding epidermal growth factor on adhesion stage of implantation.

A member of the epidermal growth factor (EGF) family, the heparin-binding EGF (HB-EGF) is expressed in the uteri of both humans and mice during the implantation process. To study the effects of HB-EGF on adhesion stage, we developed an in vitro implantation model employing Ishikawa cell line and JAR cell line, which may attach to Ishikawa cells. For 1, 6, 12, and 24 hours, co-cultures of JAR spheroids grown on Ishikawa monolayers were treated with 1, 10, and 100 ng∕mL doses of HB-EGF.

Kinetically Controlled Site-Specific Self-assembly of Hairy Colloids.

The solvophobicity-driven directional self-assembly of polymer-coated gold nanorods is a well-established phenomenon. Yet, the kinetics of this process, the origin of site-selectivity in the self-assembly, and the interplay of (attractive) solvophobic brush interactions and (repulsive) electrostatic forces are not fully understood. Herein, we use a combination of time-resolved (vis/NIR) extinction spectroscopy and finite-difference time-domain (FDTD) simulations to determine conversion profiles for the assembly of gold nanorods with polystyrene shells of distinct thicknesses into their (tip-to-tip) self-assembled structures.

Estrus Detection and Dairy Cow Identification with Cascade Deep Learning for Augmented Reality-Ready Livestock Farming.

Accurate prediction of the estrus period is crucial for optimizing insemination efficiency and reducing costs in animal husbandry, a vital sector for global food production. Precise estrus period determination is essential to avoid economic losses, such as milk production reductions, delayed calf births, and disqualification from government support. The proposed method integrates estrus period detection with cow identification using augmented reality (AR).

The effect of pharyngeal structures on the severity of obstructive sleep apnea.

Background/objective: Obstructive sleep apnea (OSA) is characterized by complete or partial cessation of breathing during sleep. The tongue is suggested as a possible anatomical site causing airway obstruction. However, the role of other pharyngeal structures in the development of OSA remains unclear.

Simultaneous UPLC Assay for Oxitropium Bromide and Formoterol Fumarate Dihydrate in Pressurized Metered Dose Inhaler Products for Chronic Obstructive Pulmonary Disease.

Backround: Oxitropium bromide (OB) and formoterol fumarate dihydrate (FFD) are inhaler molecules that are widely used in the treatment of chronic lung diseases.

Objective: The goal of this work was to create a reversed phase-ultra performance liquid chromatography (RP-UPLC) technique for assay and identification of OB and FFD, as well as identification and estimate of its associated compounds in pressurized metered dose inhaler product (pMDI).

Method: Separation of oxitropium and formoterol peaks were enhanced on a C18 (50 × 2.