Publications by authors named "Huebinger R"
Aims: Alcohol consumption along with negative sequelae from excess alcohol intake increased during the COVID-19 pandemic. We evaluated the association between binge alcohol use and long-term functional outcomes among COVID-19-positive individuals.
Methods: Using a prospective, longitudinal, multisite cohort study design, we evaluated the association between binge alcohol use and mental and physical functional outcomes using Patient-Reported Outcomes Measurement Information System (PROMIS)-29 scores three and six months postinfection.
Objectives: Antiarrhythmic administration is an important treatment for out-of-hospital cardiac arrest (OHCA) with a shockable rhythm, but little is known about disparities in such antiarrhythmic practices. We sought to investigate the association between community race/ethnicity and prehospital antiarrhythmic administration for OHCA.
Methods: We conducted a retrospective study of a national prehospital database, NEMSIS, linked to Census data.
Article Synopsis
- Burn depth determination is essential for effective patient care, but current methods lack precision; however, recent animal studies revealed that Short Wave Infrared (SWIR) imaging can effectively differentiate between superficial and deep burns.
- A study involving 11 patients utilized a SWIR assessment tool (SWAT) to compare reflectance of multiple SWIR bands with surgeons' classifications and histology results to evaluate burn depths.
- The findings indicate that while reflectance changes at certain wavelengths correlate with burn depth, multi-spectral imaging through SWAT may offer improved accuracy in assessing burn wound severity.
Objectives: Extracorporeal cardiopulmonary resuscitation (eCPR) is a promising treatment that could improve survival for refractory out-of-hospital (OHCA) patients. Healthcare systems may choose to start eCPR in the prehospital setting to optimize time to eCPR initiation and decrease low-flow time. We used geospatial modeling to evaluate different eCPR catchment strategies for a forthcoming prehospital eCPR program in Houston, Texas.
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- This study investigates how race, ethnicity, and gender affect long-term health-related quality of life in individuals who tested positive for COVID-19, focusing on changes in well-being over a three-month period.
- Among COVID-19 positive participants, Black individuals showed better cognitive function and reduced fatigue compared to non-Hispanic Whites, while females and gender diverse groups reported worse overall well-being and less improvement in fatigue.
- The findings suggest that social constructs, such as race, ethnicity, and gender, play a significant role in COVID-19 health outcomes, highlighting the need for further research in this area.
Article Synopsis
- Airway management is a crucial skill for EMS clinicians, particularly for treating pediatric patients, and this study analyzed pediatric cases using the 2019 ESO data set.
- Out of over 7 million EMS activations, 346,912 involved pediatric patients, with 27,071 encounters requiring airway management interventions such as bag-valve-mask ventilation and intubation.
- Despite the interventions, advanced airway management happened infrequently, and success rates for tracheal intubation were notably low, highlighting the need for improved training and protocols in pediatric emergency care.
Importance: Chronic symptoms reported following an infection with SARS-CoV-2, such as cognitive problems, overlap with symptoms included in the definition of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS).
Objective: To evaluate the prevalence of ME/CFS-like illness subsequent to acute SARS-CoV-2 infection, changes in ME/CFS symptoms through 12 months of follow-up, and the association of ME/CFS symptoms with SARS-CoV-2 test results at the acute infection-like index illness.
Design, Setting, And Participants: This prospective, multisite, longitudinal cohort study (Innovative Support for Patients with SARS-CoV-2 Infections Registry [INSPIRE]) enrolled participants from December 11, 2020, to August 29, 2022.
Article Synopsis
- Minoritized communities experience lower rates of initial shockable rhythm during out-of-hospital cardiac arrests (OHCA), which correlates with poorer outcomes and less favorable neurologic results than predominantly White communities.* -
- A study of over 22,000 OHCAs highlighted significant disparities in shockable rhythms: 21.1% in majority White, 15.3% in majority Black, and 16.1% in majority Hispanic/Latino communities, indicating that race/ethnicity affects OHCA outcomes.* -
- Mediation analyses showed that factors such as whether an OHCA occurred in a public location and if it was witnessed by a bystander significantly influence the likelihood of an initial shockable rhythm,
. While racial NIH funding disparities have been identified, little is known about the link between community demographics of institutions and NIH funding. We sought to evaluate the association between institution zip code characteristics and NIH funding.
View Article and Find Full Text PDFIntroduction: Data on ethnic and racial differences in symptoms and health-related impacts following SARS-CoV-2 infection are limited. We aimed to estimate the ethnic and racial differences in symptoms and health-related impacts 3 and 6 months after the first SARS-CoV-2 infection.
Methods: Participants included adults with SARS-CoV-2 infection enrolled in a prospective multicenter US study between 12/11/2020 and 7/4/2022 as the primary cohort of interest, as well as a SARS-CoV-2-negative cohort to account for non-SARS-CoV-2-infection impacts, who completed enrollment and 3-month surveys ( = 3,161; 2,402 SARS-CoV-2-positive, 759 SARS-CoV-2-negative).
Introduction: Out-of-hospital cardiac arrest (OHCA) victims in rural communities have worse outcomes despite higher rates of bystander cardiopulmonary resuscitation (CPR) than urban communities. In this retrospective cohort study we attempt to evaluate selected aspects of the continuum of care, including post-arrest care, for rural OHCA victims, and we investigated factors that could contribute to rural areas having higher rates of bystander CPR.
Methods: We analyzed 2014-2020 Texas Cardiac Arrest Registry to Enhance Survival (TX-CARES) data for adult OHCAs.
Study Objective: Airway management is a crucial part of out-of-hospital care. It is not known if the rate of overall agency intubation attempts is associated with intubation success. We sought to evaluate the association between agency intubation attempt rate and intubation success using a national out-of-hospital database.
View Article and Find Full Text PDFIntroduction: While Black individuals experienced disproportionately increased firearm violence and deaths during the COVID-19 pandemic, less is known about community level disparities. We sought to evaluate national community race and ethnicity differences in 2020 and 2021 rates of penetrating trauma.
Methods: We linked the 2018-2021 National Emergency Medical Services Information System databases to ZIP Code demographics.
Background: Traumatic brain injury (TBI) has been linked to multiple pathophysiological processes that could increase risk for Alzheimer's disease and related dementias (ADRD). However, the impact of prior TBI on blood biomarkers for ADRD remains unknown.
Objective: Using cross-sectional data, we assessed whether a history of TBI influences serum biomarkers in a diverse cohort (approximately 50% Hispanic) with normal cognition, mild cognitive impairment, or dementia.
Background Factors associated with out-of-hospital cardiac arrest (OHCA) outcome disparities remain poorly understood. We evaluated the role of receiving hospital on OHCA outcome disparities. Methods and Results We studied people with OHCA who survived to hospital admission from TX-CARES (Texas Cardiac Arrest Registry to Enhance Survival), 2014 to 2021.
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- The study examined the relationship between first responder (FR) interventions, specifically CPR and AED use, and survival outcomes after out-of-hospital cardiac arrests (OHCAs).
- Only a small number of agencies showed a positive association between FR interventions and favorable neurological survival outcomes, with CPR having fewer positive results compared to AED use.
- Agencies with better outcomes tended to handle more OHCAs but had lower rates of FR CPR and AED interventions, indicating that factors other than the frequency of intervention might influence survival rates.
Article Synopsis
- Analysts studied data from the INSPIRE registry to understand post-COVID conditions and how symptoms progress, resolve, and reemerge after SARS-CoV-2 infection.
- They examined self-reported symptoms from 1,296 adults over 12 months, finding a significant decrease in symptoms at the 3-month follow-up for both COVID test-positive (from 98.4% to 48.2%) and test-negative (from 88.2% to 36.6%) participants.
- The study revealed that symptoms can persist or reappear for up to a year after COVID-like illness, suggesting these symptoms are not only related to COVID-19 but can be associated with other illnesses as well, aiding healthcare providers in
Objective: Prior studies identified increased penetrating trauma rates during the earlier phase of the COVID-19 pandemic, but there is limited study of penetrating trauma rates in 2021 or at a national level. We evaluated trends in prehospital encounters for penetrating trauma in 2020 and 2021 using a national database.
Methods: We conducted a retrospective analysis of the National Emergency Medicinal Services (EMS) Information System (NEMSIS) combined 2018-2021 databases of prehospital encounters.
Objective: We sought to describe prehospital ultrasound (PHUS) use and trends in PHUS utilization over time using a national database.
Methods: Using the 2018 - 2021 National Emergency Medical Services Information System databases, we identified those EMS activations where PHUS was performed. We evaluated the association between year and number of PHUS exams performed using univariable and multivariable regression analysis.
Article Synopsis
- - The study addresses the issue of limited ancestral diversity in genome-wide association studies (GWAS), which makes it hard to find genetic risk variants in non-European ancestry groups, focusing on Alzheimer's Disease (AD).
- - Researchers analyzed a multi-ancestry GWAS dataset within the Alzheimer's Disease Genetics Consortium (ADGC) involving individuals from various ancestries, identifying 13 shared risk loci and 3 ancestry-specific loci, highlighting the benefits of diverse samples.
- - The findings underscore the importance of including underrepresented populations in genetic research, suggesting that even smaller sample sizes can lead to the discovery of novel genetic variants related to AD and implicating specific biological pathways like amyloid regulation and neuronal development.
Article Synopsis
- Researchers studied persistent symptoms in adults after SARS-CoV-2 infection, focusing on the types of symptoms present at 3 and 6 months post-infection using latent class analysis.* -
- The study included nearly 6,000 participants, identifying four distinct symptom groups; notably, most had minimal symptoms after 3 and 6 months, while COVID-positive individuals showed higher instances of taste/smell loss and cognitive issues.* -
- Results suggest that symptom patterns can change over time, indicating that the experience of post-COVID symptoms may be more dynamic than originally thought, with many patients shifting between symptom groups.*
Background: While prior work examining severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern focused on hospitalization and death, less is known about differences in clinical presentation. We compared the prevalence of acute symptoms across pre-Delta, Delta, and Omicron.
Methods: We conducted an analysis of the Innovative Support for Patients with SARS-CoV-2 Infections Registry (INSPIRE), a cohort study enrolling symptomatic SARS-CoV-2-positive participants.