The effect of cell therapy on the intensity of lipid peroxidation processes in the liver, kidneys and lungs of rats of different ages under conditions of experimental cranio-skeletal trauma.

Objective: Aim: To determine the effect of cell therapy on the intensity of lipid peroxidation processes in the liver, kidneys and lungs of rats of different ages under conditions of experimental cranio-skeletal trauma (CST).

Patients And Methods: Materials and Methods: In the experiments, 129 white male Wistar line rats of different age groups were used: immature rats aged 100-120 days and weighing 90-110 g; mature rats aged 6-8 months and weighing 180-200 g; and old rats aged 19-23 months and weighing 300-320 g. In each age group, CST was modeled under thiopental sodium anesthesia.

Impact of cranioskeletal trauma on the development of endogenous intoxication syndrome in rats of different ages.

Objective: Aim: The aim of the study was to determine the impact of cranioskeletal trauma (CST) on the development of endogenous intoxication syndrome in rats of different ages.

Patients And Methods: Materials and Methods: The experiments involved 147 white male Wistar rats of different age groups. The first experimental group included sexual immature rats aged 100-120 days.

ANTIOXIDANT-PROOXIDANT BALANCE OF THE KIDNEYS IN RATS OF DIFFERENT AGES UNDER CONDITIONS OF EXPERIMENTAL CRANIOSKELETAL TRAUMA.

Objective: The aim: To determine the peculiarities of the antioxidant-prooxidant balance in the kidney of rats of different ages under conditions of experimental cranioskeletal trauma (CST).

Patients And Methods: Materials and methods: The experiments involved 147 male white Wistar rats of different age groups. The first experimental group included immature animals aged 100-120 days.

THE EFFECTS OF L-ORNITINE AND L-ARGININE ON THE PROCESSES OF LIPID PEROXIDATION IN THE FUNCTIONAL LAYERS OF KIDNEYS ON THE BACKGROUND OF ACUTE TOXIC HEPATITIS.

Objective: The aim is to evaluate the effects of L-arginine and L-ornithine on the processes of lipid peroxidation in homogenates of renal cortex, renal medulla and renal papilla under conditions of acute toxic hepatitis.

Patients And Methods: Materials and methods: The study was performed on 40 outbred white male rats with experimental hepatitis, caused by carbon tetrachloride. The animals were divided into five groups: control group (the rats were simulated carbon tetrachloride poisoning and its correction by administering of olive oil and normal saline in equivalent doses), acute carbon tetrachloride hepatitis (single intraperitoneal injection of 50% carbon tetrachloride oil solution at the dose of 2 mlxkg-1 of body weight and simulation of treatment by administration of normal saline in equivalent doses), acute carbon tetrachloride hepatitis + L-ornithine (1000 mgxkg-1), acute carbon tetrachloride hepatitis + L-arginine (500 mgxkg-1) and acute carbon tetrachloride hepatitis + combination of substances.

Influence of two-hour tourniquets ischemia of limb and acute blood loss on systemic disorders of the body in the reperfusion period (experimental study).

Objective: The aim: to find out the effect of a two-hour tourniquets ischemia of the limb and acute blood loss on systemic disorders of the body in the postperfusion period.

Patients And Methods: Materials and methods: The experiments were performed on 96 nonlinear male rats weighing 200-220 g. All experiments were performed under sodium thiopental anesthesia.

Social cognitive predictors of first- and non-first-generation college students' academic and life satisfaction.

The present study tested Lent's (2004) social-cognitive model of normative well-being in a sample (N = 414) of first- and non-first-generation college students. A model depicting relationships between: positive affect, environmental supports, college self-efficacy, college outcome expectations, academic progress, academic satisfaction, and life satisfaction was examined using structural equation modeling. The moderating roles of perceived importance of attending college and intrinsic goal motivation were also explored.

[The impact of polytrauma on dynamics of late apoptosis in the tissue lymphocytes].

The changes in the late apoptosis intensity in lymphocytes, obtained from various organs under polytrauma impact, were studied in experiment. In laboratory animals of a control group the late apoptosis intensity appeared essentially bigger in pulmonary lymphocytes, comparing with those from the heart and the liver. Nonsignificant changes of intensity prolong 2 h - 3 days with essential increase in 7 days, decrease--on the 14-21th days and repeated increase--on the 28th day were characteristic in the polytrauma dynamics for late apoptosis in the lymphocytes, obtained from the lungs, the heart and the liver.

[Effect of the infusion therapy on enzymatic factor of antioxidant defense in severe combined trauma of the abdominal organs in experiment].

The influence of the infusion therapy on enzymatic link of antioxidant defense in the small bowel tissue in severe combined trauma of abdominal cavity organs was studied. The best indices of survival in 24 h and changes of the superoxiddysmutase and catalase activity in animals, to whom preparation HAES-LX5% was prescribed.

[The effect of magnetic-laser irradiation on the state of the cardiac muscle in adrenaline-induced myocardiodystrophy and food deprivation].

In experiment on white rats was evaluated the positive effect of food deprivation on heart damaged by norephynephrine. Magneto-laser irradiation increased the adaptive resources of cardiovascular system during food deprivation and norephynephrine myocardiodystrophy.

[The comparative effect of magnetic and laser irradiation of the liver and blood on the bile-secretory function in rats].

The influence of percutaneous magnetolazer irradiation of the blood and liver on the bile secretion, general bilirubin excretion and its fractions, cholesterol and bile acids rate was studied experimentally on male rats. A laser generator "Luch-2" with a magnetic nozzle (wave-length 0.82 mm, power density 0.

[The characteristics of the intracardiac and systemic hemodynamics in young, healthy, untrained subjects during physical loading of moderate intensity].

Intracardial and systemic hemodynamics have been studied in 107 healthy men aged 18-24 years during their functional rest and physical loads of 60 Wt. The echocardiographic method with hard fixation of an echo sensor was applied. Normal values of the heart functional volumes, heart output, ino- and chronotropic activity, arterial pressure and myocardial energy exchange were determined during the functional rest and under physical loads.

[Changes in the tetrapolar rheographic indices of adult and old rats under stress].

Experiments with adult (8-10 months) and old (24-26 months) male rats were carried out to investigate the effect of stress on the values of central hemodynamics and inotropic cardiac function--stroke volume, minute volume, stroke index, as well as output volume rate, output volume rate index and systolic frequency. It is found that stress causes more significant disturbance of inotropic function in old rats as compared with adult animals. This disorder occurs earlier in old rats.