Publications by authors named "Huda Fathy Ebian"
Prognostic Implications of MALAT1 and BACH1 Expression and Their Correlation with CTCs and Mo-MDSCs in Triple Negative Breast Cancer and Surgical Management Options.
Samah Said Elbasateeny Mahmoud Abdou Yassin Mohamed Mahmoud Mokhtar Adel Mohamed Ismail Huda Fathy Ebian
Int J Breast Cancer
January 2022
Article Synopsis
- Triple negative breast cancer (TNBC) is distinct from other breast cancers, lacking effective targeted treatments, prompting a study on MALAT1 and BACH1 expressions, Mo-MDSC levels, and circulating tumor cells (CTCs) to find predictive markers for surgical options.
- In a study with 88 TNBC patients, higher expressions of MALAT1 and BACH1 correlated with worse clinical outcomes, including larger tumors and more metastasis, while CTCs and Mo-MDSCs associated with poor survival rates.
- The findings suggest that upregulation of these markers in TNBC patients is linked to poorer prognoses, but those negative for either marker might have a better outlook.