Publications by authors named "Huda Ahmad Alghamdi"
Evaluating the estrogen degradation potential of laccase and peroxidase from Bacillus ligniniphilus L1 through integrated computational and experimental approaches.
Muhammad Zohaib Nawaz Syed Zeeshan Haider Liang Zhe Muhammad Usman Mirza Hafiz Rameez Khalid Huda Ahmad Alghamdi
Int J Biol Macromol
December 2024
Article Synopsis
- - This study explored how enzymes from the marine bacterium Bacillus ligniniphilus L1 can break down natural and synthetic estrogen compounds, using both computational modeling and lab experiments to assess their effectiveness.
- - Laccase from L1 demonstrated better degradation rates for compounds like estrone and estradiol valerate compared to commercial laccase, particularly when combined with the ABTS enhancer.
- - Impressively, the L1 catalase-peroxidase outperformed commercial versions in degrading various estrogen compounds, showing significant potential for practical environmental cleanup applications while supporting experimental data through molecular dynamics simulations.