Publications by authors named "Huchon C"
Article Synopsis
- Vulvar cancer primarily affects older women and requires surgical treatment, with guidelines emphasizing the importance of negative histological margins.
- A study analyzed the impact of patient age on surgical outcomes, finding that older patients (≥65 years) had larger tumors but similar rates of negative excision margins compared to younger patients (<65 years).
- Results indicated that younger patients experienced better recurrence-free survival and were more likely to undergo revision surgery despite the older group receiving more radical surgery.
Introduction: The aims of this study were to describe survival outcomes in patients with ovarian cancer aged ≥80 years and to explore predictors of poor prognosis.
Methods: We collected clinical, demographic, histologic, surgical and follow-up data for patients with ovarian cancer aged ≥80 years from a multicenter French cohort (FRANCOGYN) who underwent surgery from 1999 to 2019. Primary endpoints were overall survival (OS) and disease-free survival (DFS).
Impact of age on tumor size in vulvar cancer: A multicenter study by the Francogyn group.
Eur J Surg Oncol
September 2024
Objective: Vulvar cancer is a rare pathology affecting mainly elderly women. This study aims to evaluate the impact of age on tumor size in vulvar cancer.
Material And Methods: This was a multicenter retrospective observational study carried out between January 1, 1998, and December 31, 2020, in patients operated on for vulvar cancer.
Purpose: This study aims to assess the feasibility and efficacy of high-dose rate (HDR) brachytherapy (BT) administered in a single insertion with 4 treatment sessions for locally advanced cervical cancer and to identify the prognostic factors influencing outcomes.
Methods And Materials: We retrospectively analyzed the clinical data of patients with cervical cancer with locally advanced disease (International Federation of Gynecology and Obstetrics 2018 IB-IVB) treated at our institution from January 2014 through December 2021. Each patient received definitive radiation therapy with an external irradiation dosage between 45 and 50.
Article Synopsis
- Epithelial ovarian cancer is often diagnosed at an advanced stage, and complete cytoreductive surgery can enhance patient survival rates; the Fagotti score helps predict surgical resectability.
- * A multicenter study was conducted to assess how consistently different surgeons apply the Fagotti score when evaluating laparoscopic videos of patients with ovarian masses.
- * The results showed very good inter-observer agreement for the Fagotti score, with significant consistency among reviewers, especially when focusing on the explorable parameters of the score.
Background: Sentinel lymph node biopsy (SLNB) is commonly used in the surgical management of male breast cancer. Contrary to female breast cancer, limited data exist about its performance in male breast cancer. The objective of this systematic review and meta-analysis was to evaluate the SLNB accuracy in male breast cancer.
View Article and Find Full Text PDFObjectives: Describing the constitution of the FRANCOGYN group (a national French research group in Oncological and Gynecological Surgery) and present its current and future development.
Methods: Literature review using PUBMed database with the keyword "FRANCOGYN".
Objectives: Describing the constitution of the FRANCOGYN group (a national French research group in Oncological and Gynecological Surgery) and present its current and future development.
Article Synopsis
- - The study aims to evaluate how well surgeons and oncologists follow the European Society of Gynaecological Oncology (ESGO) guidelines for managing morbidly obese patients (BMI >40) with endometrial cancer, focusing on surgical practices, lymph node staging, and adjuvant therapies.
- - Over 2,300 patients were analyzed, revealing that only 30% of morbidly obese patients received guideline-conforming surgical management, compared to 44% of obese and 48% of normal/overweight patients; however, morbidly obese patients were more likely to receive the recommended adjuvant therapy.
- - Surprisingly, while weight status didn't affect overall survival rates, those in the morbidly obese group
Brachytherapy and surgery versus surgery alone for IB2 (FIGO 2018) cervical cancers: A FRANCOGYN study.
Eur J Obstet Gynecol Reprod Biol
November 2023
Objective: Evaluation of the management by first brachytherapy followed by radical hysterectomy (Wertheim type) compared to radical hysterectomy alone (Wertheim type) for the treatment of IB2 cervical cancer.
Methods: Data from women with histologically proven FIGO stage IB2 cervical cancer treated between April 1996 and December 2016 were retrospectively abstracted from twelve French institutions with prospectively maintained databases.
Results: Of the 211 patients with FIGO stage IB2 cervical cancer without lymph node involvement included, 136 had surgical treatment only and 75 had pelvic lymph node staging and brachytherapy followed by surgery.
Management of women with abnormal uterine bleeding: Clinical practice guidelines of the French National College of Gynaecologists and Obstetricians (CNGOF).
Eur J Obstet Gynecol Reprod Biol
September 2023
Objective: To provide French guidelines for the management of women with abnormal uterine bleeding (AUB).
Design: A consensus committee of 26 experts was formed. A formal conflict-of-interest policy was developed at the beginning of the process and enforced throughout.
Article Synopsis
- - The study compares survival and morbidity rates between two surgical approaches for advanced epithelial ovarian cancer: primary cytoreductive surgery (pCRS) and interval cytoreductive surgery (iCRS), using a matched cohort from the FRANCOGYN data.
- - Analyzing 513 patients, the results showed no significant differences in overall survival (OS) or recurrence-free survival (RFS) between the two groups, even though the pCRS group experienced higher postoperative complications.
- - Conclusions indicate that while there is no difference in survival rates, iCRS is associated with lower postoperative morbidity compared to pCRS, suggesting it may be a preferable surgical option.
Article Synopsis
- The study compares two surgical methods—hysteroscopy and vacuum aspiration—for treating incomplete spontaneous abortions, with the goal of determining which method leads to better pregnancy outcomes for women planning to conceive in the future.* -
- Conducted as a randomized controlled trial with 574 participants across 15 French hospitals, the research specifically looked at pregnancies lasting at least 22 weeks over a two-year follow-up period.* -
- Results showed no significant difference in successful pregnancy rates between the two groups, with 62.8% from the hysteroscopy group and 67.6% from the vacuum aspiration group achieving the desired outcome, suggesting that neither method proved superior in promoting future fertility.*
International Federation of Gynecology and Obstetrics (FIGO) staging classification for stage IV epithelial ovarian cancer (EOC) separates stages IVA (pleural effusion) and IVB (parenchymal and/or extra-abdominal lymph node metastases). We aimed to evaluate its prognostic impact and to compare survival according to the initial metastatic location. We conducted a multicenter study between 2000 and 2020, including patients with a FIGO stage IV EOC.
View Article and Find Full Text PDFArticle Synopsis
- The study focused on managing and understanding the survival rates of endometrial cancer patients aged 80 and older to identify indicators of poor prognosis.
- Data was collected from a French cohort, revealing that 184 out of 1647 patients treated for endometrial cancer were senior citizens, with a median overall survival of 16.4 months.
- Findings indicate that not using chemotherapy when indicated significantly correlated with worse survival outcomes, emphasizing the need for elderly patients to follow standard care guidelines for treatment.
Background/aim: The rate of local recurrence (LR) of phyllodes tumor (PT) varies from 4 to 18%. Several histological risk factors of LR of PT are known. The aim of this study was to estimate the LR rate of PT according to PT grade and to evaluate histological risk factors of PT LR in our retrospective cohort.
View Article and Find Full Text PDFThe aim of the present study was to evaluate evolution and prognosis of mucinous ovarian carcinomas (mOC), with respect to the two invasive patterns: expansile and infiltrative invasion. This was a descriptive, retrospective, multicenter study conducted in 13 French centres from 1 January 2001 to 31 December 2019. All patients operated on for epithelial ovarian neoplasia of the mucinous type (infiltrative/expansile) were included, whether the surgery was performed immediately or after neoadjuvant chemotherapy.
View Article and Find Full Text PDFPressurized intraperitoneal aerosol chemotherapy, named PIPAC, is now used in many centers around the world and as an intraperitoneal drug delivery system for treatment of peritoneal carcinomatosis. Recently, many of us have encountered problems during PIPAC procedures due to changes in material and production features of the original PIPAC nebulizer. Concomitantly, new PIPAC nebulizers proposed by other manufacturers are being launched on the market; which claim that they are the same as the original device in delivering PIPAC.
View Article and Find Full Text PDFA pre-operative radiological score to predict lymph node metastasis in advanced epithelial ovarian cancer.
J Gynecol Obstet Hum Reprod
November 2022
Background: Lymphadenectomy is part of cytoreductive surgery for patients with advanced epithelial ovarian cancer (AEOC) in case of abnormal lymph nodes before and during surgery. The aim of this study was to develop and validate a pre-operative radiological score to predict pelvic and/or para-aortic lymph node metastasis (LNM) in patients with AEOC undergoing cytoreductive surgery.
Methods: We conducted a multicentre retrospective study.
Introduction: Borderline ovarian tumours (BOT) represent 10-20% of epithelial tumours of the ovary. Although their prognosis is excellent, the recurrence rate can be as high as 30%, and recurrence in the infiltrative form accounts for 3% to 5% of recurrences. Affecting, in one third of cases, women of childbearing age, the surgical strategy with ovarian conservation is now recommended despite a significant risk of recurrence.
View Article and Find Full Text PDFImpact of severe obesity in the management of patients with high-risk endometrial cancer: A FRANCOGYN study.
J Gynecol Obstet Hum Reprod
September 2022
Objective: To assess the surgical management and survival of severely obese patients with high-risk endometrial cancer.
Materials And Methods: Data from 269 patients with high-risk endometrial cancer who were treated between 2001 and 2018 were collected from a multicenter database (11 centers). We classified the patients according to their BMI and compared outcomes in two groups: a normal weight group of women with a BMI < 25 kg/m, and a severe obesity group of women with a BMI ≥ 35 kg/m.
Article Synopsis
- This study compares the safety and outcomes of two surgical methods for staging locally advanced cervical cancer: retroperitoneal and transperitoneal para-aortic lymphadenectomy (PAAL).
- Data from 448 patients treated between 1999 and 2018 showed no significant differences in complication rates or mortality between the two methods, although the retroperitoneal approach resulted in shorter hospital stays.
- The findings suggest that retroperitoneal PAAL is a safe and effective option for nodal staging in this patient population, providing comparable outcomes to transperitoneal PAAL.
Objective: To provide French guidelines for the management of women with abnormal uterine bleeding (AUB).
Design: A consensus committee of 26 experts was formed. A formal conflict-of-interest (COI) policy was developed at the beginning of the process and enforced throughout.