Hope and depression: the mediating role of social support and spiritual coping in advanced cancer patients.

Background: Depression is the most common mental disorder in patients with advanced cancer, which may lead to poor prognosis and low survival rate. This study aims to explore the serial multiple mediating roles of social support and spiritual coping between hope and depression among patients with advanced cancer.

Methods: A cross-sectional study was conducted in China between May and August 2020.

Detection of sialic acid using boronic-acid-functionalized metal organic framework UiO-66-NH@B(OH).

Sialic acid (SA) is a crucial component of glycoproteins and glycolipids on the cellular membrane, which is essential for maintaining the function of cell membranes, such as cell recognition and communication. Simultaneously, sialic acid plays a significant role in many physiological and pathological processes. Hence, it is urgent to develop a simple and sensitive strategy for determining sialic acid.

Functionalized Metal-Organic Framework UiO-66-NH-BQB for Selective Detection of Hydrogen Sulfide and Cysteine.

Hydrogen sulfide (HS) is an important signaling molecule related to many diseases. Thus, HS has a great impact on the pathological and physiological processes in biological systems. Cysteine (l-Cys) is a building block for proteins and important metabolites.

Structural characterization and immuno-enhancing activity of a highly branched water-soluble β-glucan from the spores of Ganoderma lucidum.

A water soluble β-glucan (GLSWA-I) with a weight average molecular weight ∼1.57×10g/mol, isolated from the aqueous extract of the broken cellular wall Ganoderma lucidum spores, was purified by anion-exchange and gel-permeation chromatography. The immunological activity test in vivo showed that GLSWA-I could significantly promote dinitrochlorobenzene (DNCB) induced delayed-type ear swelling in mice.