Monotherapy vs combination therapy in patients with Klebsiella pneumoniae bloodstream infection: A systematic review and meta-analysis.

Objective: To determine whether mortality is lower in patients with Klebsiella pneumoniae bloodstream infection (BSI) who receive combination antimicrobial therapy than in those who receive monotherapy.

Methods: Two authors independently searched for relevant articles in the PubMed, Embase, Web of Science, and Cochrane Library databases through to August 10, 2023. Risk of bias was evaluated using the ROBINS-I tool.

bacteremia mortality: a systematic review and meta-analysis.

Objective: To analyze the mortality rate of patients with bacteremia (KPB) and the impact of extended spectrum beta-lactamase (ESBL) producing or carbapenem-resistance (CR) KP on the mortality rate among patients with bacteremia.

Methods: EMbase, Web of Science, PubMed, and The Cochrane Library were searched up to September 18, 2022. Two reviewers independently extracted data and evaluated risk of bias of included studies by ROBINS-I tool.