A near-infrared multifunctional fluorescent bio-probe with large stokes shift and high quantum yield for effective determination of heavy metal lead and pesticide glyphosate in vitro and vivo.

Heavy metal contamination and pesticide residues pose significant threats to human health and ecosystems. Despite its broad applications, fluorescence imaging technology often struggles in complex ecological and biological environments due to disadvantages of background autofluorescence and low quantum yield. This study introduced a near-infrared (NIR) multifunctional "off-on-off" isophorone-based fluorescent bio-probe, DHB, characterized by a high fluorescence quantum yield (10.

Classification method of traditional Chinese medicine compound decoction duration based on multi-dimensional feature weighted fusion.

This paper extends a text classification method utilizing natural language processing (NLP) into the field of traditional Chinese medicine (TCM) compound decoction to effectively and scientifically extend the TCM compound decoction duration. Specifically, a TCM compound decoction duration classification named TCM-TextCNN is proposed to fuse multi-dimensional herb features and improve TextCNN. Indeed, first, we utilize word vector technology to construct feature vectors of herb names and medicinal parts, aiming to describe the herb characteristics comprehensively.

Design, synthesis and biological activity determination of novel phenylpyrazole protoporphyrinogen oxidase inhibitor herbicides.

Protoporphyrinogen oxidase (PPO, EC 1.3.3.