Identification of the oncogenic role and clinical implication of in Colon Adenocarcinoma.

Colorectal carcinoma (CRC) is a highly prevalent and life-threatening disease with multi-stage progression, characterized by diverse molecular expression patterns at distinct stages, making treatment particularly challenging. Early detection and diagnosis of CRC are vital and can greatly benefit from the discovery of effective biomarkers. Researchers have identified novel gene signatures that play pivotal roles in specific CRC types or stages.

Effects of prebiotic supplement on gut microbiota, drug bioavailability, and adverse effects in patients with colorectal cancer at different primary tumor locations receiving chemotherapy: study protocol for a randomized clinical trial.

Background: The prevalence of colorectal cancer (CRC) worldwide is a huge challenge to human health. Primary tumor locations found to impact prognosis and response to therapy. The important role of gut microbiota in the progression and treatment of CRC has led to many attempts of alleviating chemotherapy-induced adverse effects using microecologics.

Functional Genetic Variants in SPHK1 Affect Susceptibility to Gastric Cancer in a Chinese Population.

Background: An escalating number of studies have provided identified evidence that sphingosine kinase 1 (SPHK1) plays an essential role in carcinogenesis. This present study was devised to seek the possible correlation of two tag single-nucleotide polymorphisms (SNPs) in SPHK1 (rs3744037 T>C, rs346801 C>T) with the susceptibility to gastric cancer (GC).

Methods: This present case-control study was comprised of 710 patients with GC and 710 gender- and age-matched cancer-free individuals.

Synthesis of Si/SiO core-shell nanowire arrays and broadband anti-reflection effects in diluted Si nanowire arrays by adjusting dielectric shell thickness.

A low filling ratio and enhanced absorption is needed to enable the full potential of Si nanowire (NW) arrays for optoelectronic applications. In this paper, we report a versatile, scalable fabrication technique that uses nanosphere lithography (NSL) patterning for the synthesis of vertically aligned Si and Si/SiO NW arrays. The optical reflection of the NW arrays can be substantially suppressed by the addition of the transparent shell.

On-Demand Fabrication of Si/SiO Nanowire Arrays by Nanosphere Lithography and Subsequent Thermal Oxidation.

We demonstrate the fabrication of the large-area arrays of vertically aligned Si/SiO nanowires with full tunability of the geometry of the single nanowires by the metal-assisted chemical etching technique and the following thermal oxidation process. To fabricate the geometry controllable Si/SiO nanowire (NW) arrays, two critical issues relating with the size control of polystyrene reduction and oxide thickness evolution are investigated. Through analyzing the morphology evolutions of polystyrene particles, we give a quantitative description on the diameter variations of polystyrene particles with the etching time of plasma etching.

Ti/Au Cathode for Electronic transport material-free organic-inorganic hybrid perovskite solar cells.

We have fabricated organic-inorganic hybrid perovskite solar cell that uses a Ti/Au multilayer as cathode and does not use electron transport materials, and achieved the highest power conversion efficiency close to 13% with high reproducibility and hysteresis-free photocurrent curves. Our cell has a Schottky planar heterojunction structure (ITO/PEDOT:PSS/perovskite/Ti/Au), in which the Ti insertion layer isolate the perovskite and Au layers, thus proving good contact between the Au and perovskite and increasing the cells' shunt resistance greatly. Moreover, the Ti/Au cathode in direct contact with hybrid perovskite showed no reaction for a long-term exposure to the air, and can provide sufficient protection and avoid the perovskite and PEDOT:PSS layers contact with moisture.

Is early surveillance with CT scan necessary in patients with stage II/III colorectal cancer: a retrospective study.

Background And Objectives: This analysis aims to evaluate the value of early surveillance within 6 months after resection for stage II/III colorectal cancer (CRC).

Methods: Patients with stage II/III CRC who received surgery with curative intent for CRC were included. CT scans of the chest, abdomen, and pelvis performed within 6 months after surgery were evaluated.