Lycium barbarum polysaccharide alleviates IL-1β-evoked chondrogenic ATDC5 cell inflammatory injury through mediation of microRNA-124.

Lycium barbarum polysaccharide (LBP) is a promising therapeutic drug in inflammation-related injuries, nevertheless the mechanism of LBP's action is still elusive. The study is to explore the effect of LBP on IL-1β-evoked ATDC5 cell inflammatory injury. ATDC5 cells were administrated with 10 ng/mL interleukin (IL)-1β to establish an model of cartilage damage.

Long non-coding RNA Mirt2 relieves lipopolysaccharide-induced injury in PC12 cells by suppressing miR-429.

Long non-coding RNAs (lncRNAs) and microRNAs (miRNAs) play important roles in the pathogenesis of spinal cord injury (SCI). This study investigated the effects of lncRNA Mirt2 and miR-429 on lipopolysaccharide (LPS)-induced injuries in PC12 cells. Serum samples were collected from 36 patients with SCI and the healthy controls.

[Effect of triptolide on allogenic tendon transplantation in repairing tendon defect in chicken].

Objective: Triptolide can suppress immunological rejection reaction. To investigate the effect of triptolide on allogenic tendon transplantation in repairing tendon defect in chicken.

Methods: The defect model of the third toes tendon was established in 64 healthy-cleaning male Leghorn chickens (4-month-old, weighing 1.