Loading cinnamon oil into pH-sensitive chitosan grafted mesoporous silica nanoparticles via supercritical carbon dioxide.

Stimulus-responsive mesoporous silica nanoparticles (MSNs) have displayed great potentiality for controlled-release and targeted drug delivery. In the current work, a supercritical fluid method was utilized to successfully prepare cinnamon oil loaded into chitosan grafted MSNs (CO@CS-MSNs). The influencing factors of drug loads, such as pressure, temperature, impregnation time and depressure time, were investigated.

Efficacy and safety of electroacupuncture combined with Suanzaoren decoction for insomnia following stroke: study protocol for a randomized controlled trial.

Background: Insomnia is a common but frequently overlooked sleep disorder after stroke, and there are limited effective therapies for insomnia following stroke. Traditional Chinese medicine (TCM), including acupuncture and the Chinese herbal medication (CHM) Suanzaoren decoction (SZRD), has been reported as an alternative option for insomnia relief after stroke in China for thousands of years. Here, this study aims to investigate the efficacy and safety of electroacupuncture (EA) in combination with SZRD in the treatment of insomnia following stroke.

Polarity Control within One Monolayer at ZnO/GaN Heterointerface: (0001) Plane Inversion Domain Boundary.

In semiconductor heterojunction, polarity critically governs the physical properties, with an impact on electronic or optoelectronic devices through the presence of pyroelectric and piezoelectric fields at the active heteropolar interface. In the present work, the abrupt O-polar ZnO/Ga-polar GaN heterointerface was successfully achieved by using high O/Zn ratio flux during the ZnO nucleation growth. Atomic-resolution high-angle annular dark-field and bright-field transmission electron microscopy observation revealed that this polarity inversion confines within one monolayer by forming the (0001) plane inversion domain boundary (IDB) at the ZnO/GaN heterointerface.

Adsorption of dysprosium on the graphite (0001) surface: Nucleation and growth at 300 K.

We have studied nucleation and growth of Dy islands on the basal plane of graphite at 300 K using scanning tunneling microscopy, density functional theory (DFT) in a form that includes van der Waals interactions, and analytic theory. The interaction of atomic Dy with graphite is strong, while the diffusion barrier is small. Experiment shows that at 300 K, the density of nucleated islands is close to the value predicted for homogeneous nucleation, using critical nucleus size of 1 and the DFT-derived diffusion barrier.

A ketone functionalized luminescent terbium metal-organic framework for sensing of small molecules.

A ketone functionalized luminescent terbium metal-organic framework has been realized for the highly selective and sensitive sensing of aniline.

[Efficacy comparison of different points combination in the treatment of menopausal insomnia: a randomized controlled trial].

Objective: To compare the efficacy of different points combination in the treatment of menopausal insomnia.

Methods: Ninety-six cases of menopausal insomnia were randomized into 3 groups, Xinshu (BL 15), Shenshu (BL 23), Sishencong (EX-HN 1), Shenmen (HT 7), Sanyinjiao (SP 6) were chosen in the restore interaction between the heart and the kidney group (group A, 32 cases); Zhaohai (KI 6), Jiaoxin (KI 8), Shenmai (BL 62), Pucan (BL 61) were chosen in the acupuncturing qiao mai group (group B, 32 cases); auricular Shenmen (TF4) and sensitive spot at the distribution area of auricular vagus nervus were chosen in the ear acupuncture group (group C, 32 cases). Six days made one session and the treatments were finished after 4 courses.

Strain effect on the adsorption, diffusion, and molecular dissociation of hydrogen on Mg (0001) surface.

The adsorption, diffusion, and molecular dissociation of hydrogen on the biaxially strained Mg (0001) surface have been systematically investigated by the first principle calculations based on density functional theory. When the strain changes from the compressive to tensile state, the adsorption energy of H atom linearly increases while its diffusion barrier linearly decreases oppositely. The dissociation barrier of H2 molecule linearly reduces in the tensile strain region.

Structure of the clean Gd5Ge4(010) surface.

We have characterized the (010) surface of Gd5Ge4 using scanning tunneling microscopy (STM) and x-ray photoelectron spectroscopy. Data from different samples have the following features in common: (1) the surface composition equals the bulk composition to within 5 at.%, both after ion etching and after annealing at temperatures of 400-1200 K; and (2) the surface exhibits terraces of two types.

The effect of black coral extraction on acute lung inflammation induced by cigarette smoke in mice.

Short-term exposure to cigarette smoke (CS) introduces an abundance of free radicals into the lungs, causing oxidative stress and inflammation. CS is an important risk factor related to the pathogenesis of several pulmonary diseases, especially chronic obstructive pulmonary disease. Black coral (BC) is a marine biomaterial commonly used for cigarette holders in southeast China.

Volatile constituents, inorganic elements and primary screening of bioactivity of black coral cigarette holders.

Black corals (BC) have been used for a long time in Chinese medicine, and may have some pharmaceutical functions when used as material for cigarette holders in southeast China. This study is aimed to investigate the bioactivities of volatile constituents in BC and to explore the folklore behind the use of BC cigarette holders (BCCHs). We extracted the volatile constituents of BC by supercritical fluid extraction (SFE) with carbon dioxide (CO₂-SFE), then identified and analyzed the constituents by gas chromatography-mass spectrometry (GC-MS).

Chemical composition and antifungal activity of essential oils of Thuja sutchuenensis, a critically endangered species endemic to China.

The essential oils from leaves, twigs and stems of large trees and shrub-like trees of Thuja sutchuenensis were extracted by hydrodistillation and supercritical fluid extraction, and analyzed by GC and GC-MS. The essential oil composition differed significantly among the three organs, as well as between large trees and shrub-like trees. Furthermore, consistent with the eastern Asia-North American disjunct distribution of the genus, many differences in the essential oil composition between T.

[Study on the supercritical carbon dioxide extraction of Brucea Javanica oil].

The technics of supercritical carbon dioxide extraction of Brucea Javanica for injection oil was studied. The effects of the conditions of extraction and separation on extraction oil yield and quality were investigated and the effects of extraction pressure and separation pressure on acid number of the oil were discussed. So the optimal condition of this method was determined.

[Study on extraction of zhuyun 3# by supercritical CO2].

To optimize the extraction process for zhuyun 3# pill by supercritical CO2. Five kinds of supercritical CO2 extraction method had been applied. The methods were estimated by the pharmacological results and the content of flovone.

[Supercritical CO2 extraction of fatty oils from bee pollen and its GC-MS analysis].

The extraction of fatty oils from bee pollen with supercritical CO2 was studied. The effects of extraction pressure, extraction temperature and the grinding size of the bee pollen on the yields were discussed. The optimal condition of this method was: extraction pressure 30MPa,extraction temperature 55 degrees C, separator I pressure 14MPa, separator I temperature 45 degrees C, separator II pressure 6MPa, separator II temperature 40 degrees C, extraction period 2 hours.