Publications by authors named "Huanyao Chen"
Article Synopsis
- - The study investigates factors that contribute to successful participant recruitment in randomized clinical trials (RCTs) by analyzing data from 393 completed treatment studies, focusing on accrual percentages as a measure of success.
- - A comparison of different predictive models revealed that the CatBoost regressor provided the best performance, identifying government funding and participant compensation as positive recruitment factors, while cancer-focused studies and unconventional recruiting methods were less successful.
- - The research concludes by emphasizing the importance of specific recruitment strategies, such as flexible infrastructure and adequate compensation, to enhance participant recruitment in future clinical trials.
Principal Investigators' Perceptions on Factors Associated with Successful Recruitment in Clinical Trials.
AMIA Jt Summits Transl Sci Proc
June 2023
Article Synopsis
- * Factors like trial design and sponsor influence recruitment success, but principal investigators have mixed views on how site involvement and funding affect the process.
- * Inefficient recruitment strategies are commonly used, and the study suggests improvements like better staff support and using informatics to boost recruitment efforts.
We performed a trends analysis of experimental cancer interventions. The complete records of 32,623 interventional neoplasm clinical trials involving 454 types of neoplasms from 2000 to 2017 were downloaded from the AACT database. The conditions and drug concepts were normalized using MetaMap.
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