Comparative Transcriptional Analysis of and Its -Knockout Mutant Under Galactooligosaccharides and Glucose Conditions.

Galactooligosaccharides (GOS) are documented prebiotic compounds, but knowledge of the metabolic and regulatory mechanisms of GOS utilization by lactic acid bacteria is still limited. Here we used transcriptome and physiological analyses to investigate the differences in the logarithmic growth phase of and metabolizing GOS or glucose as the sole source of carbohydrate. In total, 489 genes (16%) were differentially transcribed in the wild-type grown on glucose and GOS and the value is decreased to 7% due to the loss of .