The protective effects of triptolide on age-related bone loss in old male rats.

Background: Previous studies have showed that triptolide have a critical role in inhibiting osteoclast formation, bone resorption and attenuating regional osteoporosis. However, the protective role of triptolide on age-related bone loss has not been investigated. In the study, we assessed the effect of triptolide supplementation on bone microstructure and bone remolding in old male rat lumbars.

Effect of Bone Cement Volume Fraction on Adjacent Vertebral Fractures After Unilateral Percutaneous Kyphoplasty.

Study Design: A retrospective study.

Summary Of Background Data: Complications of the bone cement used in vertebroplasty and kyphoplasty procedures have received increasingly more attention, especially for bone cement volume.

Objective: The aim of the study was to retrospectively assess the relationship between bone cement volume fraction and adjacent vertebral fracture (AVF) after unilateral percutaneous kyphoplasty (PKP).

Emergent surgical reduction and fixation for Pipkin type I femoral fractures.

The purpose of this study was to assess the effect of timing of large fragment fixation in patients with Pipkin type-I fractures. Patients with Pipkin type-I fractures from the authors' trauma center were prospectively observed between July 2007 and July 2010. Fragments that constituted more than one-fourth of the femoral head were included.

[Screening and identification of polypeptides specifically binding to human B type natriuretic peptide from 12TM phage display peptide library].

Objective: To identify and characterize the polypeptides specifically binding to human B type natriuretic peptide (BNP) screened from 12TM phage display peptide library.

Methods: The BNP-binding peptides were screened from 12TM phage display peptide library and identified by ELISA.

Results: After 4 rounds of screening, 10 of the 16 phage clones were identified as the positive clones which could bind to BNP.