Publications by authors named "Huanhuan Hong"

The row scanning mechanism of a rolling shutter camera can be used to infer high-frequency information from a low-frame-rate video. Combining the high intensity of laser speckle and high row-sampling rate of a rolling shutter, extreme detectable vibration frequency limited by rolling shutter camera imaging is experimentally demonstrated. Using a commercially available industrial camera at a frame rate of 70 fps, a vibration signal with a frequency of 14.

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Mass spectrometry (MS) is a formidable analytical tool for the analysis of non-polar to polar compounds individually and/or from mixtures, providing information on the molecular weights and chemical structures of the analytes. During the last more than one-decade, ambient ionization mass spectrometry (AIMS) has developed quickly, producing a wide range of platforms and proving scientific improvements in a variety of domains, from biological imaging to quick quality control. These methods have made it possible to detect target analytes in real time without sample preparation in an open environment, and they can be connected to any MS system with an atmospheric pressure interface.

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According to the Report of Drug Situation in China (2020), the growth rate of the number of drug abusers in China has decreased, but the number of drug abusers is still large. An efficient screening method is necessary for controlling drug abuse. As an important type of biological sample, urine is widely used for the rapid screening of drug addicts.

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Mass spectrometry (MS) has become an essential analytical method in every sector of science and technology. Because of its unique ability to provide direct molecular structure information on analytes, an extra method is rarely required. This review describes fabrication of a variable-pressure hollow cathode discharge (HCD) ion source for MS in detection, quantification and investigation of gas-phase ion molecule reactions of explosives and related compounds using air as a carrier gas.

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In this study, we have developed a variable pressure operating hollow cathode discharge (HCD) ion source to investigate the gas phase ion-molecule reactions of nitroaromatic explosive compounds. The developed HCD ion source coupled MS system has also been validated as an analytical method to analyze explosives at trace levels. The ion source was designed in such a way that the plasma can be generated alternatively at high pressure (~30 Torr), medium pressure (~5 Torr) and low pressure (~1 Torr) regions.

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Objective: The increasing demand for unraveling cellular heterogeneity has boosted single cell metabolomics studies. However, current analytical methods are usually labor-intensive and hampered by lack of accuracy and efficiency.

Methods: we developed a first-ever automated single cell mass spectrometry system (named SCMS) that facilitated the metabolic profiling of single cells.

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In analytical science, mass spectrometry (MS) is known as a "gold analytical tool" because of its unique character of providing the direct molecular structural information of the relevant analyte molecules. Therefore, MS technique has widely been used in all branches of chemistry along with in proteomics, metabolomics, genomics, lipidomics, environmental monitoring etc. Mass spectrometry-based methods are very much needed for fast and reliable detection and quantification of drugs of abuse and explosives in order to provide fingerprint information for criminal investigation as well as for public security and safety at public places, respectively.

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