Publications by authors named "Huang Luwen"

Migraine and severe headaches are common neurological disorders with significant societal impact. Previous research indicates a potential link between serum folate levels and migraine occurrence, yet there is a lack of sufficient relevant studies and more are required. This study aimed to determine the association between a severe headache or migraine and serum folate levels in large populations.

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Objective: The associations between the ratio of blood high-sensitivity C-reactive protein (hs-CRP) to high-density lipoprotein cholesterol (HDL-C) (hs-CRP/HDL-C ratio) and outcomes in patients with acute ischemic stroke (AIS) have yet to be established. This study is the first to examine the relationship between the hs-CRP/HDL-C ratio and three-month unfavorable outcomes in patients with AIS.

Methods: This secondary analysis utilized data from a prospective cohort study involving 1559 AIS patients recruited at a South Korean hospital between January 2010 and December 2016.

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Background: Cognitive impairment, a prevalent non-motor symptom in advanced Parkinson's disease (PD), has been associated with hyperhomocysteinemia, an important risk factor for PD progression and cognitive decline in PD. However, evidence regarding the association between homocysteine (Hcy) and cognitive function during early PD remains insufficient. Therefore, this study aims to examine the correlation between Hcy levels and cognitive function in the early stage of PD.

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Background: Chronic Post-Stroke Fatigue (PSF) is a common and persistent complications among ischemic stroke survivors. The serum glycated hemoglobin (HbA1c) level, as it is known has emerged as a critical risk factor for Acute Ischemic Stroke (AIS) and post-stroke cognitive and emotional impairment. However, no studies have been conducted on the link between HbA1c and PSF.

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Background: Acute minor ischemic stroke (AMIS) has been proven to be strongly associated with post-stroke cognitive impairment (PSCI). Few studies have reported that uric acid (UA) levels are linked to PSCI in patients with AMIS, and those results are debatable. We investigated the relationship between serum UA levels and cognitive impairment in patients with AMIS.

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Article Synopsis
  • Natural blue pigments are rare and mostly replaced by synthetic ones, leading to a need for safer, natural alternatives.
  • A study optimized the production of a blue pigment from the fungus Quambalaria cyanescens using specific fermentation conditions, resulting in a high yield.
  • The blue pigment demonstrated stability under various conditions and showed antioxidant properties, with no acute toxicity observed in lab tests on a model organism.
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Article Synopsis
  • Stroke is a leading cause of health issues and even mild strokes can lead to cognitive problems, with previous studies showing mixed results on how HbA1c levels relate to cognitive decline.
  • The study analyzed data from 311 patients who had acute mild ischemic strokes to explore the relationship between their HbA1c levels and cognitive impairment using a specific assessment scale.
  • Results indicated a nonlinear relationship, where HbA1c levels above 8.2% were linked to an increased risk of post-stroke cognitive impairment, highlighting the importance of monitoring this blood sugar marker in stroke patients.
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Objective: To determine whether the methylenetetrahydrofolate reductase () C677T gene polymorphism is linked to the risk of ischaemic stroke and circulating homocysteine (Hcy) levels in a Chinese population.

Methods: This case-control study recruited angiogram-diagnosed patients with ischaemic stroke and healthy control subjects. The plasma Hcy concentrations were measured and the C677T gene polymorphism was genotyped.

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In this research, a simple, green and effective strategy was developed to produce long-term stable oil in water emulsion from soy protein and soy polysaccharide. Soy protein and soy polysaccharide formed dispersible complexes at pH around 3.25 aqueous solution through electrostatic and hydrophobic interactions.

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