Radioablation settings affecting the size of lesions created ex vivo in porcine livers with monopolar perfusion electrodes.

Rationale And Objectives: To explore the morphological characteristics of ablated lesions and find which combination of duration, temperature, and power was preferable to create largest lesion size with monopolar perfusion electrodes.

Materials And Methods: Using monopolar perfusion electrodes to create 72 lesions in 30 excised porcine livers with radiofrequency radiation at different durations (5, 10, 15, and 20 minutes), temperatures (83 degrees C, 93 degrees C, 103 degrees C, and 113 degrees C), and powers (20, 30, and 40 W). Lesion volumes were calculated from longitudinal diameters and transverse diameters.

Noninvasive treatment of malignant bone tumors using high-intensity focused ultrasound.

Background: High-intensity focused ultrasound (HIFU) is a new, noninvasive technique with potential to ablate and inactivate tumors. Treatment of solid tumors with HIFU has been reported. In this study, the safety and effects of HIFU in the clinical therapy of malignant bone tumors were assessed.

Influence of intense pulsed light on the secretion of TGF-beta1 in cultured human fibroblasts and intervention of JNK inhibitor.

Objective: To determine the influence of intense pulsed light (IPL) on the secretion of TGF-beta1 in cultured human fibroblasts and the intervention of JNK inhibitor.

Methods: The callan foreskin fibroblasts were cultured and divided into 2 groups. In the IPL treatment group, cells were irradiated with IPL with fluences of 0 (negative control), 10, 18, 27, 36, and 36 J/cm2*2 (irradiated with IPL with fluences of 36 J/cm2 twice).

[Experimental study of the effect of radiofrequency ablation with series of WHK-3 conformable electrode in ex vivo ox liver].

Objective: To evaluate the conformablity and quantization controllability of multi-cluster conformable radiofrequency ablation electrode by ex vivo animal experiment.

Methods: The subject using in this experiment were fresh ex vivo ox liver. The electrode we used were the series of WHK-3 (including WHK-3 I and II), which were design and made by Welfare Electronic Technological Company (Beijing).

[Experimental radiofrequency ablation in porcine liver ex vivo with "wet" unipolar electrode].

Objective: To observe the effects of radiofrequency ablation in porcine liver ex vivo with "wet" RITA UniBlate unipolar electrode, evaluate the morphologic characteristic of the ablated zones and explore the impact upon the ablation lesions of time, temperature and set power of "wet" monopolar electrodes.

Methods: The maximal effective ablation electrode length of this "wet" unipolar electrode is 2.5 cm.

Comprehensive sequential interventional therapy for hepatocellular carcinoma.

Background: Since the 1980s, various approaches to interventional therapy have been developed, with the development and achievement of medical imaging technology. This study aimed to evaluate the effectiveness of comprehensive sequential interventional therapy especially personal therapeutic plan in 53 radical cure patients with hepatocellular carcinoma (HCC).

Methods: From January 2003 to January 2005, a total of 203 patients with HCC received sequential interventional treatment in our hospital.

[Clinical value of percutaneous ethanol ablation in complicated renal carcinoma].

Objective: To probe clinical value of percutaneous ethanol ablation (PEA) in complicated renal carcinoma.

Methods: 10 cases complicated renal carcinoma patients with 16 lesions ranged from 1.7-8.

The first organic-templated vanadyl(IV) gallophosphates with ambient (51)V hyperfine structure, {V(2)Ga(2)O(14)} cluster or heterometal 12-ring channels.

Three new vanadyl gallium phosphates, (H(2)dap)(3)[(VO)(2)(GaO)(2)(PO(4))(4)].H(2)O (1), (H(2)dap)(1.5)[(VO)(2)(GaO)(2)(PO(4))(3)].

Electrochemical quartz crystal microbalance study of covalent tethering of carboxylated thiol to polyaniline for electrocatalyzed oxidation of ascorbic acid in neutral aqueous solution.

The electrochemical quartz crystal microbalance (EQCM) was used to study the electrosyntheses and electrochemical properties of two kinds of polyaniline (PANI)-thiol composite films in aqueous solutions, which were prepared by covalent binding of a thiol to the oxidized forms of PANI (PANI(post)-thiol, protocol A), and electropolymerization of aniline in the presence of a thiol (PANI(poly)-thiol, protocol B), respectively. The thiols involved were mercaptosuccinic acid (MSA), thioglycolic acid (TGA) and beta-mercaptoethanol (ME). The PANI(post)-thiol binding processes were monitored in situ with the EQCM, giving molar binding ratios (r, thiol vs.

[Experimental study of CT-guided percutaneous ethanol ablation in rabbit renal VX2 tumor].

Background And Objective: CT-guided percutaneous ethanol ablation (PEA) has been widely used in treating solid tumors such as hepatoma, lung cancer, adrenal nonfunctional adenoma. This study was to explore the efficacy, safety and feasibility of CT-guided PEA in treating renal tumor in rabbit.

Methods: Twenty-five rabbits carrying VX2 tumor were randomized into PEA group (15 rabbits) and control group (10 rabbits).

[Clinical effect of transcatheter arterial chemoembolization combined with high intensity focused ultrasound ablation in treatment of large hepatocellular carcinoma].

Objective: To investigate the clinical effect of transcatheter arterial chemoembolization (TACE) combined with high intensity focused ultrasound (HIFU) ablation in treatment of large hepatocellular carcinoma (HCC).

Methods: Sixty-eight patients with unresectable HCC were randomized into 2 age, tumor size, TNM stages, and liver function grade-matched groups: TACE group (n=30) undergoing TACE and TACE+HIFU group (n=38) undergoing 2-3 weeks after TACE. A total of 88 tumors (9.

Application of multislice spiral CT angiography on transcatheter arterial chemoembolization for hepatocellular carcinoma.

Background And Objective: Multislice spiral CT angiography (MSCTA) is very important in the diagnosis and treatment of liver diseases. Currently, most studies on three-dimensional MSCTA of the liver vascular system focus on the liver tumors, preoperative assessment of liver transplantation and the systematic anatomy of the liver vascular system. This study was to investigate the clinical application of MSCTA on transcatheter arterial chemoembolization (TACE) for hepatocellular carcinoma (HCC) by comparing images of MSCTA and digital subtraction angiography (DSA).

Effect and mechanism of intense pulsed laser on skin aging in rats.

Objective: To explore the effect of intense pulsed laser (IPL) on anti-aging and its mechanism.

Methods: Rat skin was continuously irradiated ex vivo by IPL at certain wavelengths with different energy densities. The rats were irradiated twice with an interval of 2 weeks.

Osteosarcoma: limb salvaging treatment by ultrasonographically guided high-intensity focused ultrasound.

The purpose of this study was to prospectively evaluate the use of ultrasonographically guided high-intensity focused ultrasound (HIFU) in the salvage of limbs in patients with osteosarcoma. Seven patients underwent HIFU ablation. Laboratory and radiologic examinations were performed after intervention.

[CT-guided percutaneous ethanol ablation in the treatment of malignancies with pleural or chest wall invasion].

Objective: To explore the feasibility and efficiency of CT-guided percutaneous ethanol ablation (PEA) in the treatment of malignant tumors with pleural or chest wall invasion.

Methods: Nine patients of malignant tumors with pleural or chest wall invasion that failed to respond to operation, radiotherapy, or chemotherapy were treated by PEA under CT guidance. The improvement of quality of life (QOL) during the treatment was observed and the efficiency was evaluated by CT scan.

Biofuel cell and phenolic biosensor based on acid-resistant laccase-glutaraldehyde functionalized chitosan-multiwalled carbon nanotubes nanocomposite film.

To immobilize laccase (Lac) from Trametes versicolor that shows its maximum enzymatic activity in acidic aqueous solutions, the biopolymer chitosan (CS) was chemically modified with glutaraldehyde (GA) to form GA functionalized CS (GAfCS), which was then allowed to react with Lac to form a Lac-GAfCS composite that is robust in weakly acidic solutions (two-step protocol), as confirmed by quartz crystal microbalance and durability tests. The Lac-GAfCS-multiwalled carbon nanotubes (MWCNTs)/glassy carbon (GC) electrode exhibited good catalytic activity towards O(2) reduction in the presence of 2,2'-azinobis (3-ethylbenzothiazoline-6-sulfonate) diammonium salt (ABTS), and the pH-dependent enzymatic activity of the immobilized Lac towards O(2) reduction was examined. A glucose/air biofuel cell was fabricated, with the Lac-GAfCS-MWCNTs/GC electrode as the biocathode and a glucose oxidase (GOx)-GAfCS-MWCNTs/GC electrode as the bioanode in a Nafion membrane-separated acetate buffer solution (pH 5.

Fabrication of antireflective sub-wavelength structures on silicon nitride using nano cluster mask for solar cell application.

We have developed a simple and scalable approach for fabricating sub-wavelength structures (SWS) on silicon nitride by means of self-assembled nickel nanoparticle masks and inductively coupled plasma (ICP) ion etching. Silicon nitride SWS surfaces with diameter of 160-200 nm and a height of 140-150 nm were obtained. A low reflectivity below 1% was observed over wavelength from 590 to 680 nm.

[Percutaneous radiofrequency ablation in treatment of advanced local lung cancer: clinical analysis of 78 cases].

Objective: To investigate the efficacy and safety of radiofrequency ablation (RFA) in treatment of advanced lung cancer.

Methods: Seventy-eight patients with advanced local lung cancer were treated with RFA at the temperature from 70 degrees C to 90 degrees C under local or intravenous anesthesia under CT scan for 8 minutes to 26 minutes. 103 times of RFA were done in 78 patients, 19 of them being treated twice and 2 treated tree times.

[Clinical value of CT guided radiofrequency ablation in treatment of post-operational resectable liver metastatic tumor from colorectal carcinoma].

Objective: To explore the value of CT guided radiofrequency ablation (RFA) in treatment of post-operational resectable liver metastatic tumors from colorectal carcinoma.

Methods: Thirty-seven patients with 52 resectable liver metastatic tumors from colorectal carcinoma underwent CT guided RFA. CT, MRI, ultrasonography, and/or PET/CT were conducted after RFA every 2 months.

[Interventional management of severe complications after percutaneous transhepatic cholangic drainage and percutaneous implantation of biliary stents].

Objective: To evaluate the efficacy of interventional management in treatment of severe complications after percutaneous transhepatic cholangiography and percutaneous implantation of biliary stents.

Methods: Percutaneous biliary drainage and implantation of biliary stents for malignant biliary obstruction under fluoroscopic guidance was performed in 113 patients. Thirteen of them developed severe complications: drainage catheter slipping and locating between liver and abdominal in 4 cases, bowl obstruction due to lower implantation or slipping of stent into the duodenum in 4 cases, and plenty of bloody drainage in 5 cases.

[Influence of neutrophils from severe burn patients on morphology and function of vascular endothelial cells and the protective effect of intervention with Shenmai concoction].

Objective: To study the influence of neutrophils from severe burn patient on the morphology and function of vascular endothelial cells (VEC), and the protective effect of Shenmai concoction on VEC.

Methods: Neutrophils were isolated from the venous blood of healthy volunteers and burn patients [at 6, 24, 48 post burn hour (PBH)], and they were cocultured with VECs (ECV304) in vitro. The viability of VECs was assessed by MTT.

[CT guided 125I seeds implantation in treatment of local recurrent rectal cancer after surgery resection: analysis of 21 cases].

Objective: To explore the clinical value of CT guided 125I seeds implantation in the treatment of local recurrent rectal cancer after surgery resection.

Methods: Twenty-one patients with local recurrent rectal cancer after surgery, 12 males and 9 females, aged 47 (35-69), with the longest diameter of 4. 2 cm (3.

[Short-term efficacy of ct-guided radioactive seed 125I implantation on residual or relapsing metastatic lymph nodes in advanced tumor patients after multi-modality treatment].

Background & Objective: Lymph node metastasis is an important factor affecting tumor staging, treatment and prognosis. Residual or newly developed metastatic lymph nodes after combined therapy will bring difficulty in further treatment for cancer patients. This study was to investigate the clinical value of CT-guided radioactive seed 125I implantation in treating metastatic lymph nodes.

Radiofrequency ablation as a treatment for hilar cholangiocarcinoma.

Aim: To explore the role of radio-frequency ablation (RFA) as a treatment for hilar cholangiocarcinoma.

Methods: Eleven patients with obstructive cholestasis underwent Computed Tomography (CT) examination, occupying lesions were observed in the hepatic hilar region in each patient. All lesions were confirmed as cholangioadenocarcinoma by biopsy and were classified as type III or IV by percutaneous transhepatic cholangiography.

[mRNA and protein expression of haptoglobin in lesions of condyloma acuminatum].

Objective: To investigate the expression of haptoglobin in the lesions of condyloma acuminatum (CA) at the mRNA and protein level, and to explore its role in the pathogenesis of CA.

Methods: The expressions of haptoglobin protein and mRNA in the skin tissues of 30 patients with CA and 20 normal controls were detected by immunohistochemistry(IHC), Western blot, and hybridization in situ.

Results: The in situ hybridization study showed that haptoglobin mRNA was expressed in the epidermal cells in the lesions of CA.