Publications by authors named "Huancheng Zheng"

Article Synopsis
  • Alzheimer's disease (AD) primarily affects the elderly and is linked to the decline of the ubiquitin proteasome system (UPS), critical for maintaining protein balance in cells.
  • The study focused on UBE2O, an important part of the UPS, finding that its expression decreases with age and is significantly lower in AD-affected brain regions compared to healthy brains.
  • Enhancing UBE2O levels could potentially reduce neuronal death associated with AD, suggesting it may be a promising treatment target.
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Background: Even though a fair amount of studies focus on depression among college students, the effect of perceived parenting styles on the incidence of major depressive disorder (MDD) among representative freshmen in Chinese context is scarcely studied. The aim of this study is to investigate the effect of parenting styles on MDD in Chinese freshmen.

Methods: A total of 9,928 Chinese freshmen were recruited in 2018.

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Multiple risk factors of stroke are associated with telomere length shortening. Although leukocyte telomere length (LTL) is shorter in patients with stroke, the heterogeneity is high. Risk factors may be differentially associated with LTL in male and female patients contributing to the heterogeneity.

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Diabetic foot, a main complication of diabetes mellitus, renders the foot susceptible to infection, and may eventually lead to non-traumatic limb amputation due to the deterioration of diabetic foot ulcers (DFUs). Characterizing the pathogen spectrum and antibiotic susceptibility is critical for the effective treatment of DFUs. In the current study, the characteristics and antibiotic susceptibility of the pathogen spectrum were analyzed.

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Objective: To evaluate the effects of continuous blood purification on the hemodynamics and oxygenation in patients with acute respiratory distress syndrome (ARDS).

Methods: Twenty-one patients with ARDS were treated with continuous veno-venous hemofiltration (CVVH) combined with plasma exchange. Hemodynamics and oxygenation were measured or calculated at scheduled intervals using Swan-Ganz catheters.

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