Interferon Regulatory Factors (, , , and ) in Sichuan taimen (): Identification and Functional Characterization.

: Interferon regulatory factors (IRFs) are multifunctional transcription factors that play important roles in the transcriptional regulation of interferons and in the immune response to pathogens. Therefore, studying the interferon system in fish is highly relevant in the prevention and treatment of viral diseases. : In this study, five IRF genes (, , , and ) were identified and characterized in , and their expression profiles were determined after LPS and Poly(I:C) treatment.

Metagenomic Sequencing Elucidated the Microbial Diversity of Rearing Water Environments for Sichuan Taimen ().

Background: Sichuan taimen () is a fish species endemic to China's upper Yangtze River drainage and has significant value as an aquatic resource. It was listed as a first-class state-protected wild animal by the Chinese government due to its very limited distribution and wild population at present.

Methods: To elucidate the diversity of microorganisms in rearing water environments for , metagenomic sequencing was applied to water samples from the Maerkang and Jiguanshan fish farms, where were reared.

Identification, expression and molecular polymorphism of T-cell receptors α and β from the glacial relict Hucho bleekeri.

The T-cell receptor (TCR) is a specific molecule on the surface of all T cells that mediates cellular adaptive immune responses to antigens. Hucho bleekeri is a critically endangered species and is regarded as a glacial relict that has the lowest-latitude distribution compared with any Eurasian salmonid. In the present study, two TCR genes, namely, TCR α and β, were identified and characterized in H.

Full-length transcriptome sequencing and identification of immune-related genes in the critically endangered Hucho bleekeri.

Hucho bleekeri is a glacial relict and critically endangered fish restricted to the Yangtze River drainage in China. The lack of basic genomic information and immune characteristics will hinder the way toward protecting this species. In the present study, we conducted the first transcriptome analysis of H.