Systematic assessment of transcriptomic and metabolic reprogramming by blue light exposure coupled with aging.

The prevalent use of light-emitting diodes (LEDs) has caused revolutionary changes in modern life, but the potential hazards to health of blue light are poorly understood. N-methyladenosine (mA) is the most prevalent posttranscriptional modification in eukaryotes and can modulate diverse physiological processes by regulating mRNA fate. Here, to understand the effects and molecular mechanisms of daily low-intensity blue light exposure (BLE) and ascertain whether mA methylation plays a role in BLE-induced phenotypes, we constructed a series of models under different durations of daily low-intensity BLE and obtained multiomics profiles.

Gut Microbiota Dysbiosis Influences Metabolic Homeostasis in .

Insect gut microbiota plays important roles in acquiring nutrition, preventing pathogens infection, modulating immune responses, and communicating with environment. Gut microbiota can be affected by external factors such as foods and antibiotics. (Lepidoptera: Noctuidae) is an important destructive pest of grain crops worldwide.