Publications by authors named "Huan-zhang Shao"
Background: Blue rubber blister nevus syndrome (BRBNS) is a congenital, rare disease characterized by venous malformations of the skin and internal organs, affecting all systems throughout the body. The pathogenesis is unknown. There is no consensus on the treatment of BRBNS.
View Article and Find Full Text PDFArticle Synopsis
- Distal metastases significantly lower the prognosis for colorectal cancer patients, with around 95% of these cancers being DNA mismatch repair proficient (pMMR).
- Previous research indicates that the microRNA miR-6511b-5p is less expressed in pMMR cases, but its specific role in cancer metastasis remained unclear.
- Experimental studies showed that miR-6511b-5p can inhibit metastasis by reducing the expression of CD44 through direct interaction with BRG1, suggesting it could serve as a potential biomarker and treatment target for metastatic pMMR colorectal cancer.