Publications by authors named "Huan-Xi Zhang"
Article Synopsis
- The study evaluates the external predictability of various population pharmacokinetic (popPK) models for mycophenolate mofetil (MMF) used in kidney transplant patients taking tacrolimus.
- Using an independent dataset, the study assessed model performance through prediction diagnostics, simulation checks, and Bayesian forecasting, leading to the identification of factors influencing predictability.
- Results indicated significant variability and poor predictive performance across models, highlighting the importance of therapeutic drug monitoring for MMF and the need for further research to understand key influencing factors.
Background: Accumulating studies on computational fluid dynamics (CFD) support the involvement of hemodynamic factors in artery stenosis. Based on a patient-specific CFD model, the present study aimed to investigate the hemodynamic characteristics of transplant renal artery stenosis (TRAS) and its alteration after stent treatment.
Methods: Computed tomography angiography (CTA) data of kidney transplant recipients in a single transplant center from April 2013 to November 2014 were reviewed.
Early graft loss and poor graft function limit the use of kidneys from infant donors. Six en bloc kidney transplantations were performed from infant donors younger than 10 months into pediatric recipients between November 2012 and September 2015 at our center. We retrospectively analyzed recipient and donor demographics, surgery procedures, complications, graft function and size, and patient and graft survival with a follow-up of 6-39 months (median 15.
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