A global product of 150-m urban building height based on spaceborne lidar.

Urban building height, as a fundamental 3D urban structural feature, has far-reaching applications. However, creating readily available datasets of recent urban building heights with fine spatial resolutions and global coverage remains a challenging task. Here, we provide a 150-m global urban building heights dataset around 2020 by combining the spaceborne lidar (Global Ecosystem Dynamics Investigation, GEDI), multi-sourced data (Landsat-8, Sentinel-2, and Sentinel-1), and topographic data.

Serological proteomic profiling uncovered CDK5RAP2 as a novel marker in benign prostatic hyperplasia.

Background: Benign prostatic hyperplasia (BPH) affects approximately half of men over the age of 50. Early detection and timely treatment facilitate disease intervention and achieve a better clinical outcome. However, current clinical methods, such as prostate specific antigen (PSA), lack the sensitivity to accurately distinguish between BPH and prostate cancer (PCa).

Enhanced stability of curcumin encapsulated in fish gelatin emulsions combined with γ-Polyglutamic acid.

This study examined the rheological properties, interfacial characteristics, particle size, zeta potential, Turbiscan stability index (TSI), morphology, and encapsulation efficiency of curcumin (Cur) loaded fish gelatin (FG) emulsions modified with γ-polyglutamic acid (γ-PGA). The results showed that adding γ-PGA significantly increased curcumin encapsulation efficiency. At 0.

sp. nov., a novel actinobacterium isolated from the gill of the leopard coral grouper ().

A novel actinomycete, designated strain ZYX-F-249, was isolated from the gill of a leopard coral grouper in Yongxing Island, Hainan Province, China. Based on 16S rRNA gene sequence analysis, strain ZYX-F-249 belonged to the genus , with high similarities to ATCC 12950 (98.7 %), 211020 (98.

Site-specific drug release of monomethyl fumarate to treat oxidative stress disorders.

Treatment of diseases of oxidative stress through activation of the antioxidant nuclear factor E2-related factor 2 (NRF2) is limited by systemic side effects. We chemically functionalize the NRF2 activator monomethyl fumarate to require Baeyer-Villiger oxidation for release of the active drug at sites of oxidative stress. This prodrug reverses chronic pain in mice with reduced side effects and could be applied to other disorders of oxidative stress.

Thermal stability of γ-PGA modified fish gelatin emulsion.

Background: Emulsions are thermally unstable systems. This research aimed to investigate the thermal stability of fish gelatin (FG) oil-in-water emulsions in the presence of poly-γ-glutamic acid (γ-PGA) as an additive after heat treatment. The study assessed how γ-PGA influences the thermal stability of FG emulsions over time, focusing on their properties, structure, and food application potential.

Solar energy powered electrochemical reduction of CO on InO nanosheets with high energy conversion efficiency at a large current density.

Electrochemical CO reduction (ECOR) to value-added chemicals offers a promising approach to both mitigate CO emission and facilitate renewable energy conversion. We demonstrate a solar energy powered ECOR system operating at a relatively large current density (57 mA cm) using InO nanosheets (NSs) as the cathode and a commercial perovskite solar cell as the electricity generator, which achieves the high solar to formate energy conversion efficiency of 6.6 %.

Porous Bi Nanosheets Derived from β-BiO for Efficient Electrocatalytic CO Reduction to Formate.

The electrochemical CO reduction reaction (ECORR) is a promising strategy for converting CO into high-value chemical products. However, the synthesis of effective and stable electrocatalysts capable of transforming CO into a specified product remains a huge challenge. Herein, we report a template-regulated strategy for the preparation of a BiO-derived nanosheet catalyst with abundant porosity to achieve the expectantly efficient CO-to-formate conversion.

Fragmentation Patterns of Phenolic C-Glycosides in Mass Spectrometry Analysis.

Background: Many phenolic C-glycosides possess nutritional benefits and pharmacological efficacies. However, the MS/MS fragmentation pattern of phenolic C-glycosides analysis is understudied. This paper aims to determine the MS/MS fragmentation patterns of phenolic C-glycosides.

Development and validation of a sensitive LC-MS/MS assay of GT-14, a novel Gα2 inhibitor, in rat plasma, and its application in pharmacokinetic study.

A sensitive and selective LC-MS/MS method was developed and validated for the quantitation of a novel Gα2 inhibitor, GT-14, in rat plasma using a SCIEX 6500+ triple QUAD LC-MS system equipped with an ExionLC UHPLC unit. GT-14 (m/z 265.2 → 134.

Utilization and value-adding of waste: Fabrication of porous material from chitosan for phosphate capture and energy storage.

Efficient removal and recycling of phosphorus from complex water matrices using environmentally friendly and sustainable materials is essential yet challenging. To this end, a novel bio-based adsorbent (DX-FcA-CS) was developed by coupling oxidized dextran-crosslinked chitosan with ferrocene carboxylic acid (FcA). Detailed characterization revealed that the incorporation of FcA reduced the total pore area of DX-FcA-CS to 7.

Development of a TaqMan Real-Time PCR for Early and Accurate Detection of Anthracnose Pathogen in .

Anthracnose, caused by , is a destructive disease of in southern China. Early and proper monitoring and quantification of is of importance for disease control. A calmodulin () gene-based TaqMan real-time PCR assay was developed for efficient detection and quantification of , which reliably detected as low as 5 pg of genomic DNA and 12.

Characterization of VOC emissions and health risk assessment in the plastic manufacturing industry.

Volatile organic compounds (VOCs) significantly contribute to ozone pollution formation, and many VOCs are known to be harmful to human health. Plastic has become an indispensable material in various industries and daily use scenarios, yet the VOC emissions and associated health risks in the plastic manufacturing industry have received limited attention. In this study, we conducted sampling in three typical plastic manufacturing factories to analyze the emission characteristics of VOCs, ozone formation potential (OFP), and health risks for workers.

Rheology, physicochemical properties, and microstructure of fish gelatin emulsion gel modified by γ-polyglutamic acid.

In this work, the effect of the addition of γ-polyglutamic acid (γ-PGA) on the rheology, physicochemical properties, and microstructure of fish gelatin (FG) emulsion gel was investigated. Samples of the emulsion gel were evaluated for rheological behavior and stability prior to gelation. The mechanical properties and water-holding capacity (WHC) of the emulsion were determined after gelation.

An optimized short-term steroid therapy for chronic drug-induced liver injury: A prospective randomized clinical trial.

Background And Aims: The use of corticosteroids in chronic drug-induced liver injury (DILI) is an important issue. Our previous randomized controlled trial showed that patients with chronic DILI benefited from a 48-week steroid stepwise reduction (SSR) regimen. However, it remains unclear whether a shorter course of therapy can achieve similar efficacy.

Multiscale structure changes and mechanism of polyphenol-amylose complexes modulated by polyphenolic structures.

This study was designed to investigate the effect of polyphenolic structure on the interaction strength and process between polyphenols (gallic acid (GA), epigallocatechin gallate (EGCG) and tannic acid (TA)) and amylose (AM). The results of Fourier transform infrared spectroscopy, isothermal titration calorimetry, X-ray photoelectron spectroscopy and molecular dynamic simulation (MD) suggested that the interactions between the three polyphenols and AM were noncovalent, spontaneous, low-energy and driven by enthalpy, which would be enhanced with increasing amounts of pyrogallol groups in the polyphenols. The results of turbidity, particle size and appearance of the complex solution showed that the interaction process between polyphenols and AM could be divided into three steps and would be advanced by increasing the number of pyrogallol groups in the polyphenols.

Disulfidptosis characterizes the tumor microenvironment and predicts immunotherapy sensitivity and prognosis in bladder cancer.

Background: Bladder cancer (BLCA) is prone to metastasis and has poor prognosis with unsatisfactory treatment responsiveness. Disulfidptosis is a recently discovered, novel mode of cell death that is closely associated with human cancers. However, a comprehensive analysis of the relationship between disulfidptosis and BLCA is lacking.

IgG antibody response to SARS-CoV-2 infection and its influencing factors in lymphoma patients.

Background: The ability of generating effective humoral immune responses to SARS-CoV-2 infection has not been clarified in lymphoma patients. The study aimed to investigate the antibody (Ab) production after SARS-Cov-2 infection and clarify the factors affecting the Ab generation in these patients.

Patients & Methods: 80 lymphoma patients and 51 healthy controls were included in this prospective observational study.

Value of preoperative controlling nutritional status score in prognosis of patients with high-risk factors for early-stage cervical cancer.

Objective: To investigate whether the preoperative controlling nutritional status (COUNT) score is a prognostic factor of patients with high-risk factors for early-stage cervical cancer after surgery and concurrent chemoradiotherapy (CCRT).

Methods: This was a retrospective study. From July 2017 to March 2021, a total of 354 patients with histologically confirmed FIGO stage IB-IIA cervical cancer undergoing surgery and postoperative CCRT were included at Hunan University of Medicine General Hospital, China.

A dynamic nomogram for predicting intraoperative brain bulge during decompressive craniectomy in patients with traumatic brain injury: a retrospective study.

Objective: The aim of this paper is to investigate the risk factors associated with intraoperative brain bulge (IOBB), especially the computed tomography (CT) value of the diseased lateral transverse sinus, and to develop a reliable predictive model to alert neurosurgeons to the possibility of IOBB.

Methods: A retrospective analysis was performed on 937 patients undergoing traumatic decompressive craniectomy. A total of 644 patients from Fuzong Clinical Medical College of Fujian Medical University were included in the development cohort, and 293 patients from the First Affiliated Hospital of Shantou University Medical College were included in the external validation cohort.

Leveraging an efficient preparation method into magnetic resonance examinations of young children aged 3-6.

Purpose: To evaluate the benefits of a multifaceted concept, ANMTE (Appropriate Number of children, appropriate learning Methods, appropriate adaptive Training, and appropriate Encouragement), proposed by our group, in improving the success rate, efficiency and image quality of Magnetic Resonance (MR) examinations for children from 3 to 6 years old.

Method: In this study, 150 participants were included from July 2019 to January 2023, including 50 non-sedated children in ANMTE group, 50 in the group with sedative, and 50 in the group with routine preparations. ANMTE refers to appropriate number of children, appropriate learning methods, appropriate adaptive training, and appropriate encouragement, developed by our group for MR examinations of children from 3 to 6 years old.

The Value of Sports and Functional Exercise on Preventing Falls in Elderly Patients with Cognitive Impairment: A Systematic Review and Meta-Analysis.

Objective: To explore the value of sports and functional exercises in preventing falls in elderly patients with cognitive impairment.

Methods: PubMed, EMBASE, Cochrane Library, China National Knowledge Infrastructure, VIP, Wanfang Database, and China Biomedical Literature Database (CBM), from inception to January 2023, were used to search the randomized controlled trials (RCTs) of sports and functional exercises in elderly patients with cognitive impairment. Two independent researchers extracted the data and evaluated the quality of the included literature.