Publications by authors named "Huan W Yang"
Article Synopsis
- Lawsonia intracellularis is the cause of proliferative enteropathy (PE) in various mammals, including pigs and horses, and its effects on the innate immune response were not well understood before this study.
- The research focused on the NF-κB pathway and found that its activation increased significantly at 5 days post-infection (dpi) with this bacterium, particularly with a vaccine strain, leading to elevated expression of immune response genes like IL-6, IFN-γ, and IL-8.
- The findings suggest a link between higher NF-κB signaling and bacterial load, with the vaccine strain showing reduced cell viability and slight differences in immune response compared to a clinical strain.
