Publications by authors named "Huan Minh Tran"

Introduction: This systematic review examines how extreme temperatures impact chronic obstructive pulmonary disease (COPD) morbidity and mortality, focusing on identifying vulnerable subpopulations.

Methods: We conducted a systematic literature search from January 1, 2000, to November 6, 2024, across databases like PubMed, MEDLINE and EMBASE, Web of Science, and Scopus, focusing on observational studies that quantitatively defined extreme temperatures and their impacts on COPD morbidity and mortality. Out of 3140 records, 25 studies met the inclusion criteria.

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Objective: This study investigates the associations of α1-antitrypsin, inter-α-trypsin inhibitor heavy chain (ITIH4), and 8-isoprostane with lung function in shipyard workers exposed to occupational metal fume fine particulate matter (PM), which is known to be associated with adverse respiratory outcomes.

Methods: A 3-year follow-up study was conducted on 180 shipyard workers with 262 measurements. Personal exposure to welding fume PM was collected for an 8-h working day.

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Article Synopsis
  • This study investigates the role of blood biomarkers in predicting acute exacerbations (AEs) in patients with chronic obstructive pulmonary disease (COPD), focusing on different inflammatory phenotypes.
  • Researchers analyzed data from 340 COPD patients, categorizing them into eosinophilic inflammation (EOCOPD) and non-eosinophilic inflammation (N-EOCOPD) groups to examine blood cell counts and health outcomes.
  • The findings suggest that different white blood cell profiles can aid in assessing the risk of exacerbations in COPD patients, highlighting an increased risk associated with higher neutrophil-to-lymphocyte ratios in EOCOPD patients and a decreased risk with higher eosinoph
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The impact of short-term exposure to environmental factors such as temperature, relative humidity (RH), and fine particulate matter (PM) on chronic obstructive pulmonary disease (COPD) remains unclear. The objective of this study is to investigate PM as a mediator in the relationship between short-term variations in RH and temperature and COPD severity. A cross-sectional study was conducted on 930 COPD patients in Taiwan from 2017 to 2022.

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Background: Climate change plays a significant role in global health threats, particularly with respiratory diseases such as chronic obstructive pulmonary disease (COPD) and asthma, but the long-term global-scale impact of climate change on these diseases' mortality remains unclear.

Objective: This study aims to investigate the impact of climate change on the age-standardized mortality rates (ASMR) of COPD and asthma at national levels.

Methods: We used Global Burden of Disease (GBD) data of ASMR of COPD and asthma from 2000 to 2018.

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Article Synopsis
  • Air pollution is linked to chronic obstructive pulmonary disease (COPD), and this study aimed to explore how it mediates the health impacts of climate factors on COPD patients in Taiwan.
  • The research involved 117 COPD patients, measuring various health outcomes and their connections to relative humidity, temperature, and air pollution over different time periods.
  • Key findings indicate that increases in relative humidity and temperature can improve lung function and reduce emphysema, while higher levels of air pollutants reduce lung function and oxygen saturation, highlighting the significant health risks posed by climate change-related air pollution.
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